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This study aims to characterize dynamic stability disorders in two conditions mainly affecting the elderly and with similar walking deficits: hydrocephalus at normal pressure and Parkinson's disease, to provide the most relevant monitoring criteria in usual care.
Walking disorders in normal pressure hydrocephalus are manifested by slowing and ataxic gait, similar to disorders in Parkinson's disease. No studies in the literature have focused on advanced measures of dynamic stability in hydrocephalus at normal pressure, compared to Parkinson's disease, on large samples. The Laboratory of Analysis and Restoration of Movement, located in a Neurorehabilitation Department, provides quantitative data on gait and in particular dynamic stability as part of additional assessments to help patients follow up. Since 2010, people with normal pressure hydrocephalus or Parkinson's disease regularly benefit from these assessments. Retrospective analysis of all these data would help to better characterize motor disorders in hydrocephalus at normal pressure, by discriminating them from those associated with Parkinson's disease. It would lead to the definition of relevant indices to be used for patient follow-up.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Normal pressure hydrocephalus | Patients with a diagnosis of normal pressure hydrocephalus and who performed a gait analysis in laboratories |
| |
| Parkinson's disease | Patients with a diagnosis of Parkinson's disease and who performed a gait analysis in laboratories |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dynamic stability measurement | Diagnostic Test | The subject is asked to walk 8 meters 3 times: at free speed, at fast speed, and with large steps. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Coefficient of variation in step length | Coefficient of variation in step length during 8-meter comfortable walking test | 30 seconds |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with normal pressure hydrocephalus or Parkinson's disease.
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| Name | Affiliation | Role |
|---|---|---|
| Emilie Hutin | Henri Mondor University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Laboratoire Analyse et Restauration du Mouvement | Créteil | France |
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| ID | Term |
|---|---|
| D006849 | Hydrocephalus |
| D010300 | Parkinson Disease |
| D051346 | Mobility Limitation |
| D009069 | Movement Disorders |
| D020234 | Gait Ataxia |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020734 | Parkinsonian Disorders |
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| D001480 | Basal Ganglia Diseases |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001259 | Ataxia |
| D020820 | Dyskinesias |
| D009461 | Neurologic Manifestations |
| D020233 | Gait Disorders, Neurologic |