IMPACT: Investigating Mild Cognitive Impairment in Patients And Controls With TD-fNIRS
IMPACT: Investigating Mild Cognitive Impairment in Patients And Controls With TD-fNIRS
The goal of the proposed observational, multi-site study is to use fNIRS neurophysiological data recorded during a battery of tasks to detect MCI within a cohort consisting of patients and age-matched healthy controls. Furthermore, the investigators aim to explore whether they can measure the severity of MCI symptoms in the patient population. If successful, this approach enables clinicians to track the disease at its source-the brain; possibly allowing for earlier detection of MCI and its progression, and ultimately more efficient interventions.
Inclusion Criteria:
Patients
Healthy Controls
Exclusion Criteria:
Patients
Alzheimer's or dementia diagnosis
Current substance or alcohol dependence, and/or alcohol or substance abuse as determined by CAGE-AID assessment for drug and alcohol abuse. A score of 2 or higher would result in exclusion.
Has uncorrected major visual or auditory deficits that would prevent them from completing a study task
Current or recent (in the past 6 months) chemotherapy and/or radiation for any cancer
Major medical illnesses and psychiatric conditions (other than MCI) including:
Healthy Controls
Prior MCI or memory impairment diagnosis
First-degree relative with dementia or clinically relevant memory problems
Alzheimer's or dementia diagnosis
Current substance or alcohol dependence, and/or alcohol or substance abuse as determined by CAGE-AID assessment for drug and alcohol abuse. A score of 2 or higher would result in exclusion.
Has uncorrected major visual or auditory deficits that would prevent them from completing a study task
Current or recent (in the past 6 months) chemotherapy and/or radiation for any cancer
Major medical illnesses and psychiatric conditions including: