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The purpose of this study is to evaluate the mass balance and safety of [14C] ABBV-903 in healthy male volunteers following a single oral dose administration.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ABBV-903 | Experimental | Participants will receive ABBV-903 on Day 1. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ABBV-903 | Drug | Solution; Oral |
|
| Measure | Description | Time Frame |
|---|---|---|
| Maximum observed concentration (Cmax) of ABBV-903 | Cmax of ABBV-903 will be assessed. | Up to Day 16 |
| Time to Cmax (peak time, Tmax) of ABBV-903 | Tmax of ABBV-903 will be assessed. | Up to Day 16 |
| Terminal Phase Elimination Half-life (t1/2) of ABBV-903 | Terminal phase elimination half-life (t1/2) will be assessed. | Up to Day 16 |
| Area Under the Plasma Concentration-time Curve (AUC) from Time 0 to the Time of the Last Measurable Concentration (AUC0-t) of ABBV-903 | AUC0-t of ABBV-903 will be assessed. | Up to Day 16 |
| AUC from Time 0 to Infinite Time (AUC0-t) of ABBV-903 | AUC0-inf of ABBV-903 will be assessed. | Up to Day 16 |
| Number of Participants with Adverse Events (AEs) | An adverse event (AE) is defined as any untoward medical occurrence in a patient or clinical investigation participant administered a pharmaceutical product which does not necessarily have a causal relationship with this treatment. | Baseline to Day 46 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| ABBVIE INC. | AbbVie | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fortrea Clinical Research Unit Inc. /ID# 253962 | Madison | Wisconsin | 53704 | United States |
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