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| Name | Class |
|---|---|
| Fire Brigade Of Paris Emergency Medicine Dept | OTHER |
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Out-of-hospital cardiac arrest (OHCA) is a major public health problem, with around 40,000 victims each year in France. Their survival rate remains dramatically low, at less than 10%.
In the event of pre-hospital cardiac arrest, rescuers perform resuscitation techniques using equipment for which they have been trained. They perform cardiopulmonary resuscitation (CPR) by alternating 30 chest compressions with 2 insufflations (30/2) with a manual insufflator bag.
In basic life supports, insufflations should result in chest rise, but guidelines do not specify a precise volume.
Recently, medical devices have been developed that enable precise measurement of ventilatory volumes. In simulation, these devices show hyperventilation in volume and frequency in mannequins. But no clinical study has analyzed insufflator bag ventilation maneuvers in real-life situations on pre-hospital cardiac arrest patients.
The aim of this study is to analyze ventilation parameters in current practice in relation to standards, and the factors influencing the quality of ventilation maneuvers.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EOLIFE | Device | Measurement of ventilatory parameters during manual ventilation by professional rescuers during out-of-hospital cardiac arrest |
| Measure | Description | Time Frame |
|---|---|---|
| Tidal volume | Measurement of volume (mL) provided by the BLS Teams [air + oxygen] for each manual insufflation performed by the rescuer | up to 20 minutes (end of BLS-CPR) |
| Measure | Description | Time Frame |
|---|---|---|
| chest rise | concomitant chest rise (YES/NO) during each ventilation procedure | up to 20 minutes (end of BLS-CPR) |
| Ventilation rate | Ventilation rate per min. achieved by the rescuer |
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Inclusion Criteria:
Exclusion Criteria:
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Civilian population in hyperurban areas
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| Name | Affiliation | Role |
|---|---|---|
| Frederic Lemoine, NP | Paris Fire Brigade Emergency Dept | Principal Investigator |
| Stephane Travers, MD PhD | Paris Fire Brigade Emergency Dept | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Paris Fire Brigade | Paris | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41237844 | Derived | Lemoine F, Jost D, Lemoine S, Petermann A, Salome M, Tassart B, Liscia J, Briche F, Bon O, Derkenne C, Frattini B, Travers S; Paris Fire Brigade Cardiac Arrest Task Force (collaborators). Manual bag-valve-mask ventilation during out-of-hospital cardiopulmonary resuscitation: a prospective observational study. Resuscitation. 2025 Dec;217:110895. doi: 10.1016/j.resuscitation.2025.110895. Epub 2025 Nov 12. |
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| ID | Term |
|---|---|
| D058687 | Out-of-Hospital Cardiac Arrest |
| D006323 | Heart Arrest |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| up to 20 minutes (end of BLS-CPR) |
| Insufflation time | Insufflation time (seconds) per ventilation procedure | up to 20 minutes (end of BLS-CPR) |
| Face mask leakage | face mask leakage per ventilation procedure | up to 20 minutes (end of BLS-CPR) |
| Volume received by the patient | Volume received (mL) by the patient per ventilation procedure | up to 20 minutes (end of BLS-CPR) |
| Survival to day 60 after cardiac arrest | Survival curve over the first 60 days | up to 60 days |