Dose of Remi in Children

Determination of the 50% and 95% Effective Dose of Remimazolam for Intravenous Anesthesia Induction in Pediatric Patients

Remimazolam has demonstrated the potential as a valuable medication for procedural sedation and general anesthesia. However, the effective dosage of remimazolam in pediatric patients is still unknown.

Inclusion Criteria:

• age from 3 to 12 years old
• patients scheduled for surgery under general anesthesia

Exclusion Criteria:

• American Society of Anesthesiologists status >=Ⅲ
• Body mass index>=28kg/m2
• patients who cannot cooperate with intravenous anesthesia induction
• patients with risk of difficult airway
• patients who are allergic to benzodiazepines
• patients with delayed neurologic function