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To assess melon and oil olive pressed candy on skin condition improvement
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo candy | Placebo Comparator |
| |
| melon and oil olive pressed candy | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo candy | Dietary Supplement | consume 2 tablets per day |
| |
| Measure | Description | Time Frame |
|---|---|---|
| The change of skin wrinkles | VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units | Change from Baseline skin wrinkles at 12 weeks |
| The change of skin texture | VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units | Change from Baseline skin texture at 12 weeks |
| The change of skin melanin index | Mexameter® MX18 was utilized to measure skin melanin index. Units: arbitrary units | Change from Baseline skin melanin index at 12 weeks |
| The change of skin erythema index | Mexameter® MX18 was utilized to measure skin erythema index. Units: arbitrary units | Change from Baseline skin erythema index at 12 weeks |
| The change of skin L* value | Chroma Meter MM500 was utilized to measure skin L* value. Units: arbitrary units | Change from Baseline L* value at 12 weeks |
| The change of skin b* value | Chroma Meter MM500 was utilized to measure skin b* value. Units: arbitrary units | Change from Baseline b* value at 12 weeks |
| The change of skin ITA° value | Chroma Meter MM500 was utilized to measure skin ITA° value. Units: arbitrary units | Change from Baseline ITA° value at 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| The change of TEAC of blood | Venous blood was sampled to measure TEAC | Change from Baseline TEAC at 12 weeks |
| The change of SOD of blood | Venous blood was sampled to measure SOD |
| Measure | Description | Time Frame |
|---|---|---|
| The change of self-assessment skin and hair condition | A self-assessment questionnaire was collected to evaluate skin and hair condition | Change from Baseline skin and hair condition at 12 weeks |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Chia-Hua Liang, Prof. | Chia Nan University of Pharmacy & Science | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chia Nan University of Pharmacy & Science | Tainan | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39927597 | Derived | He Y, Bu Y, Chiang CF, Lin YH, Liang CH, Chan LP, Sun J. Multi-Plant Concentrated Powder Improved Skin Whitening: A Double-Blinded, Randomized, and Placebo-Controlled Clinical Study. J Cosmet Dermatol. 2025 Feb;24(2):e70011. doi: 10.1111/jocd.70011. |
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| ID | Term |
|---|---|
| D012871 | Skin Diseases |
| ID | Term |
|---|---|
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D000069463 | Olive Oil |
| ID | Term |
|---|---|
| D004042 | Dietary Fats, Unsaturated |
| D004041 | Dietary Fats |
| D005223 | Fats |
| D008055 | Lipids |
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| melon and oil olive pressed candy |
| Dietary Supplement |
consume 2 tablets per day |
|
|
| The change of skin spots | VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units | Change from Baseline skin spots at 12 weeks |
| The change of skin UV spots | VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units | Change from Baseline skin UV spots at 12 weeks |
| The change of skin brown spots | VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units | Change from Baseline skin brown spots at 12 weeks |
| Change from Baseline SOD at 12 weeks |
| The change of GSH-Px of blood | Venous blood was sampled to measure GSH-Px | Change from Baseline GSH-Px at 12 weeks |
| D005224 |
| Fats, Unsaturated |
| D010938 | Plant Oils |
| D009821 | Oils |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |