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The goal of this observational study is to evaluate the effects of a supervised aerobic exercise training program on weight loss, functional capacity, quality of life (QoL), and depression levels in patients with essential hypertension.
Patients who chose the treatment type according to personal preferences were divided into two groups: Group 1(n:91) exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory, and group 2(n:47) was advised to maintain dietary habits and physical activity levels. Body weight, serum lipid levels, functional capacity, QoL, and depression level of all the participants were evaluated at baseline and 6 weeks later.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 | Group 1 exercised for six weeks, involving once per day, five sessions per week under the supervision of a medical doctor, and a nurse in the aerobic exercise laboratory. The aerobic exercise training program lasted six weeks, and patients lived in the hospital for the whole period. Aerobic exercise training was performed on cycle ergometers (Ergoline, ergoselect II 100/200/Reha, Germany) equipped with a computed ergometer and developed to monitor electrocardiography (ECG), heart rhythm, and BP. Each session consisted of a 5-minute warm-up, followed by 50 minutes of aerobic exercise with an intensity of 50% to 70% of heart rate reserve, calculated by Karvonen formula, and ended with a 5-min cool-down period. |
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| Group 2 | The subjects assigned to the control group (Group 2) were advised to maintain dietary habits and physical activity levels and the aerobic exercise program was provided to them after completing the study. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Supervised Aerobic Exercise | Other | Group 1 exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory. |
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| Measure | Description | Time Frame |
|---|---|---|
| Body weight | kilograms | was measured at the pre-treatment period and the post-treatment 6th week for all the participants by the same physician. |
| Blood samples | Serum total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, and triglycerides | Twelve-hour fasting blood samples were collected between 6.00 am, and 10.00 am at baseline and week 6. |
| The functional capacity | The 6MWT test and the estimated metabolic equivalents or METs were used performed to evaluate functional capacity. | 6MWT was assessed in face-to-face interviews before and immediately after the treatment was completed. |
| Quality of Life | Quality of life was assessed with Short Form-36 (SF-36). | SF36 was assessed in face-to-face interviews before and immediately after the treatment was completed. |
| Depression level | Depression level was assessed Beck Depression Inventory (BDI). | BDI was assessed in face-to-face interviews before and immediately after the treatment was completed. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with Essential Hypertension
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Selcuk University Faculty of Medicine | Konya | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D000075222 | Essential Hypertension |
| ID | Term |
|---|---|
| D006973 | Hypertension |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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