Nano Fat Injection With or Without Fractional Carbon Diox... | NCT05985265 | Trialant

Nano Fat Injection With or Without Fractional Carbon Diox... | NCT05985265 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Nano fat grafting and fractional carbon dioxide laser resurfacing	Experimental	treating of atrophic acne scars with nano fat and fractional carbon dioxide laser	Procedure: Fat grafting

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Fat grafting	Procedure	Nano fat grafting followed by fractional carbon dioxide laser resurfacing	Nano fat grafting and fractional carbon dioxide laser resurfacing

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Clinical assessment of acne scar severity	as assessed using the Goodman and Baron Qualitative scar grading system before and after treatment on both sides of face, to determine the number of patients achieving two grades improvement vs one grade or no improvement	up to 24 weeks

Secondary Outcomes

Measure	Description	Time Frame
Physician global assessment	two blinded observers will compare the before and after photographs separately on each facial side and will evaluate the improvement on a quartile grading scale as: poor,<25% improvement; fair, 25%-50% improvement; good, 51%-75% improvement; and excellent, >75% improvement.	up to 24 weeks

Contacts/Locations Module

Overall Officials

Name	Affiliation	Role
youssef S farrag, MD	Department of Plastic Surgery, professor	Principal Investigator
Wael S Ibraheem, MD	Department of Plastic Surgery , Assistant lecture	Principal Investigator

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
17199653	Background	Goodman GJ, Baron JA. Postacne scarring: a qualitative global scarring grading system. Dermatol Surg. 2006 Dec;32(12):1458-66. doi: 10.1111/j.1524-4725.2006.32354.x.
11423843	Result	Jacob CI, Dover JS, Kaminer MS. Acne scarring: a classification system and review of treatment options. J Am Acad Dermatol. 2001 Jul;45(1):109-17. doi: 10.1067/mjd.2001.113451.