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To conduct a retrospective study to examine the effect of these conservative treatments to the symptoms and quality of life of patients with urinary incontinence. The investigators will use both subjective and objective assessment parameters, such as self-report symptoms, bladder diary, pad test and urodynamic study to access the improvement.
Urinary incontinence is a common problem among women. The main types include stress incontinence, urge incontinence, and overflow incontinence. Other underlying pathology, such as cancer or neurologic disease can also cause urinary incontinence. To limit the medical expenses and possible complications of surgical treatment, the current treatment guidelines recommend conservative treatment as the first choice. According to American Urological Association (AUA)/Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU) guidelines, the first-line treatment for non-neurologic overactive bladder should be behavioral therapy, such as bladder training, water restriction, and pelvic floor muscle training, physiological feedback, pessary, etc. Bladder training aims to increase the time interval between voids, and to increase the bladder capacity by self-adjusted schedules. Pelvic floor muscle training strengthens the pelvic floor muscles to provide urethral support to prevent urine leakage and suppress urgency. There is strong evidence that pelvic floor muscle training is beneficial for stress urinary incontinence.
The second-line treatment is medication, including anticholinergic drugs and ß3 adrenoceptor-acting agents. Anticholinergic drugs can reduce bladder detrusor contraction, and ß3 adrenoceptor-acting agents can relax the detrusor and increase bladder capacity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bladder training (BT) | Data obtained before and after the training. |
| |
| biofeedback-assisted pelvic floor muscle training (bPFMT) | Data obtained before and after the training. |
| |
| intra-vaginal electric stimulation (iVES) | Data obtained before and after the training. |
| |
| BT+bPFMT | Data obtained before and after the training. |
| |
| BT+iVES | Data obtained before and after the training. |
| |
| bPFMT+iVES | Data obtained before and after the training. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| BT | Procedure | A program of BT (including exercise and muscle training) |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Urodynamic study (intravesical pressure) | intravesical pressure (cmH2O) | form the baseline to the post-treatment measurement (about 6 month post) |
| Urodynamic study (abdominal pressure) | abdominal pressure (cmH2O) | form the baseline to the post-treatment measurement (about 6 month post) |
| Urodynamic study (detrusor pressure) | detrusor pressure (cmH2O) | from the baseline to the post-treatment measurement (about 6 month post) |
| Urodynamic study (Infused volume) | infused volume (ml) | from the baseline to the post-treatment measurement (about 6 month post) |
| Urodynamic study (voided volume) | voided volume (ml) | from the baseline to the post-treatment measurement (about 6 month post) |
| Pad test | The weight of Pad (g) before and after testing | from the baseline to the post-treatment measurement (about 6 month post) |
| Bladder diary (voiding frequency) | the daily voiding frequency (times) | from the baseline to the post-treatment measurement (about 6 month post) |
| Bladder diary (voiding volume) |
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Inclusion Criteria:
Exclusion Criteria:
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Diagnosed at Mackay Memorial Hospital, the adult female patient was clinically assessed and diagnosed with urinary incontinence. Non-surgical treatments were administered, followed by subsequent monitoring and follow-up.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hui-Hsuan Lau, M.D. | Contact | +886-975-835928 | huihsuan1220@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Hui-Hsuan Lau, M.D. | Department of Ear, Nose, and Throat, MacKay Memorial Hospital, Taipei, Taiwan | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Obstetrics and Gynecology | Recruiting | New Taipei City | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34453426 | Background | Denisenko AA, Clark CB, D'Amico M, Murphy AM. Evaluation and management of female urinary incontinence. Can J Urol. 2021 Aug;28(S2):27-32. | |
| 31609735 | Background | Wallace SL, Miller LD, Mishra K. Pelvic floor physical therapy in the treatment of pelvic floor dysfunction in women. Curr Opin Obstet Gynecol. 2019 Dec;31(6):485-493. doi: 10.1097/GCO.0000000000000584. |
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For we uncertain if this might violate personal information laws in our country.
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| ID | Term |
|---|---|
| D014549 | Urinary Incontinence |
| ID | Term |
|---|---|
| D014555 | Urination Disorders |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| bPFMT |
| Procedure |
A bPFMT program at home |
|
| iVES | Procedure | An iVES program at home |
|
| BT + bPFMT | Procedure | Combination of BT and bPFMT |
|
| BT + iVES | Procedure | Combination of BT and iVES |
|
| bPFMT + iVES | Procedure | Combination of bPFMT and iVES |
|
the daily voiding volume (ml)
| from the baseline to the post-treatment measurement (about 6 month post) |
| Questionaire (UDI-6) | The urogenital distress inventory-6 (UDI-6) | from the baseline to the post-treatment measurement (about 6 month post) |
| Questionaire (IIQ-7) | incontinence impact questionnaire-7 (IIQ-7) | from the baseline to the post-treatment measurement (about 6 month post) |
| 28681849 | Background | Aoki Y, Brown HW, Brubaker L, Cornu JN, Daly JO, Cartwright R. Urinary incontinence in women. Nat Rev Dis Primers. 2017 Jul 6;3:17042. doi: 10.1038/nrdp.2017.42. |
| 30545535 | Background | Lin HY, Tsai HW, Tsui KH, An YF, Lo CC, Lin ZH, Liou WS, Wang PH. The short-term outcome of laser in the management of female pelvic floor disorders: Focus on stress urine incontinence and sexual dysfunction. Taiwan J Obstet Gynecol. 2018 Dec;57(6):825-829. doi: 10.1016/j.tjog.2018.10.010. |
| 39170685 | Derived | Lau HH, Lai CY, Hsieh MC, Peng HY, Chou D, Su TH, Lee JJ, Lin TB. Effect of intra-vaginal electric stimulation on bladder compliance in stress urinary incontinence patients: the involvement of autonomic tone. Front Neurosci. 2024 Aug 7;18:1432616. doi: 10.3389/fnins.2024.1432616. eCollection 2024. |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D059411 | Lower Urinary Tract Symptoms |
| D020924 | Urological Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |