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Low back pain (LBP) is the largest cause of morbidity in the world, and about 80% of Chinese people are affected in their lifetime. Although the prevalence of IDD gradually increases with age, IDD is very common among subjects under 30 years old. In addition to age, there are other factors, such as excessive or uneven mechanical load, obesity, genetics, nutrition, trauma and gender. In addition, it is not clear whether the heavy physical load associated with occupation is an important risk factor for IDD. Some studies have found that IDD is more common among athletes than the general population. Due to the complexity and multifactorial nature of IDD, its pathogenesis and risk factors are still unclear, which seriously hinders the rational stratification of LBP patients and limits the development of personalized treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| pirffmann 2 grade |
| ||
| pirffmann 3 grade |
| ||
| pirffmann 4 grade |
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| pirffmann 5 grade |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CXCL2/CXCL8 | Diagnostic Test | Detecte CXCL2/8 content in nucleus pulposus and peripheral blood of patients in each group |
|
| Measure | Description | Time Frame |
|---|---|---|
| CXCL2/8 content | CXCL2/CXCL8 content of nucleus pulposus | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with lumbar disc herniation who went to the spinal surgery department of Zhongda Hospital
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zhongda Hospital | Recruiting | Nanjing | Jiangsu | China |
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| ID | Term |
|---|---|
| D055959 | Intervertebral Disc Degeneration |
| ID | Term |
|---|---|
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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