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The primary objective of this study was to evaluate time effect on the clinical predictability of collagen matrix Xenograft (CMX) with melatonin gel versus connective tissue graft (CTG) and determine whether it is proposed to be an alternative in multiple adjacent gingival recession (MAGR) in recession type one (RT1)
this study was conducted to evaluate time effect on the clinical predictability of collagen matrix Xenograft (CMX) with melatonin gel versus connective tissue graft (CTG) and determine whether it is proposed to be an alternative in multiple adjacent gingival recession
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| collagen matrix | Experimental | melatonin in collagen matrix with Modified Coronally Advanced Tunneling Technique (MCAT) |
|
| connective tissue graft (CTG) | Active Comparator | connective tissue graft with Modified Coronally Advanced Tunneling Technique (MCAT) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| melatonin with collagen matrix | Combination Product | (CMX) with melatonin in the esthetic zone using Modified Coronally Advanced Tunneling Technique (MCAT) |
|
| Measure | Description | Time Frame |
|---|---|---|
| interproximal clinical attachment level | measured from CEJ to base of pocket depth by using periodontal prob | 6-9 months |
| Probing pocket depth (PPD) | from gingival margin to pocket depth measured by mm | 6-9 months |
| Recession depth | measure from CEJ to gingival margin by mm | 6-9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Keratinized tissue width | from free gingival groove to MGJ | 6-9 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ain Shams University | Cairo | Cairo Governorate | 11566 | Egypt |
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| ID | Term |
|---|---|
| D008550 | Melatonin |
| ID | Term |
|---|---|
| D014363 | Tryptamines |
| D007211 | Indoles |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
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| connective tissue graft (CTG) | Combination Product | control group connective tissue graft using Modified Coronally Advanced Tunneling Technique (MCAT) |
|
| D006571 | Heterocyclic Compounds |
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |