A Combinatorial Biomarker for Infection Diagnosis in Children

A Combinatorial Biomarker for Infection Diagnosis in Children

To describe the epidemiology, clinical presentation, diagnosis, therapy, and treatment outcomes of patients in whom the combination biomarker BV (combination of TRAIL, IP-10, and CRP) is used, and to compare them with control patients without BV measurement.

Secondary objectives:

• Qualitative evaluation of indication as well as adherence to the test result.
• Comparison of antimicrobial therapy, performed diagnostics, hospitalization, and outcomes between patients with high BV score (bacterial) and patients with low BV score (viral).

Inclusion Criteria:

• Suspicion of acute bacterial or viral infection
• Requirement of at least one BV test during medical presentation

Exclusion Criteria:

• lack of informed consent