PET-CT Predicting Lymph Nodes Metastasis

The Value of PET-CT in Predicting Lymph Nodes Metastasis in Non Small Cell Lung Cancer

This study is a single-center prospective clinical study that aims to evaluate the predictive value of preoperative 18F-FDG-PET-CT and 18F-FAPI-PET/CT for lymph node metastasis in patients with non-small cell lung cancer. The final pathological results were used to assess the predictive value of PET-CT for lymph node metastasis.

Inclusion Criteria:

• Solitary tumor, or multiple tumors with only ground-glass nodules (GGNs) apart from the primary lesion.
• Diameter of the primary lesion ≤5cm, with a CTR between 0.5 and 1.
• Pathological confirmation of non-small cell lung cancer (NSCLC) either before or during surgery.
• No prior radiotherapy or chemotherapy for initial treatment.
• No history of malignant tumors.

Exclusion Criteria:

• Locally advanced or distant metastasis.
• Pleural dissemination observed during surgery.
• History of malignant tumors.
• Received neoadjuvant therapy.
• Histopathological examination reveals lung malignancies other than non-small cell lung cancer (NSCLC).