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| Name | Class |
|---|---|
| Royal Marsden NHS Foundation Trust | OTHER |
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Myeloma is a bone marrow cancer with over 5000 patients diagnosed in the UK each year. Researchers are committed to improving understanding of myeloma and developing more effective treatments with fewer side effects in order to improve patient outcomes. In order to do this, researchers are collecting samples of blood and bone marrow to test the activity of potential new treatments in the laboratory and to understand what may be the cause of some treatments not working.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Participants with a diagnosis, or suspected diagnosis, of myeloma or related plasma cell disorder | Participants who are undergoing peripheral blood or bone marrow aspirate sampling for diagnostic, staging or follow-up purposes, before, whilst or after receiving anti-myeloma treatment will be approached to collect additional samples for research. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observational study - sample collection only. | Other | No intervention - blood and/or bone marrow sample collection only |
|
| Measure | Description | Time Frame |
|---|---|---|
| Cell viability | Myeloma cell viability when incubated with standard of care and novel compounds. | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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Participants who have a diagnosis, or suspected diagnosis, of myeloma or related plasma cell disorder
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Disco Team | Contact | 020 3186 5275 | Disco.iras263630@nhs.net |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Royal Marsden NHS Foundation Trust | Recruiting | Sutton | SM25PT | United Kingdom |
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| ID | Term |
|---|---|
| D009101 | Multiple Myeloma |
| ID | Term |
|---|---|
| D054219 | Neoplasms, Plasma Cell |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D020141 | Hemostatic Disorders |
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| D014652 |
| Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D010265 | Paraproteinemias |
| D001796 | Blood Protein Disorders |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D006474 | Hemorrhagic Disorders |
| D008232 | Lymphoproliferative Disorders |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |