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Dry eye disease (DED) is a growing public health concern affecting quality of life and visual function, with a significant socio-economic impact. It is more prevalent in the females and is being specifically in the menopausal and postmenopausal age group.
Bioptron light therapy is efficient in the elimination of allergic reactions, signs and symptoms of dry eye improving capillary circulation, immunity stimulation, relieving pain and establishing balance of tissue electromagnetic field
Around 60 postmenopausal women will be randomly divided into two equal groups, they all complain from dry eye symptoms, ranging from mild/normal to moderate and severe.
Group(A): will receive patient education program for four weeks. Group(B): will receive patient education program and bioptron light therapy for four weeks
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| education program group | No Intervention | this group will receive patient education program for four weeks.
| |
| bioptron light therapy group | Experimental | Patients will be sitting in a comfortable chair, with their eyes closed, with cleaned eyelids, and occasionally blinking. Bioptron lamp will be lined at an angle of 90°, at a distance from 5 cm to 10 cm, exposure time will be 5 min. Energy is very low, 1 - 2.4 J/cm without thermal effects, energy density is 40mW. Bioptron light is polychrome, wave frequency is from 400 nm (including blue, visible radiation) up to 2000 nm (representing infrared waves) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| bioptron light therapy | Device | patients will receive patient education program and bioptron light therapy for four weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| Dry Eye-Related Quality-Of-Life Score (DEQS) | The Dry Eye-Related Quality-Of-Life Score questionnaire is a 15-item instrument for assessing subjective dry eye symptoms and their effects on activities of daily living within the previous week.
| Dry Eye-Related Quality-Of-Life Score will be measured at baseline, and it will be measured again after four weeks |
| Tear Breakup Time (TBUT) | Tear Breakup Time Is the time interval between a complete blink and the appearance of the first break, discontinuity or dry spot observed in the tear film. | Tear Breakup Time will be measured at baseline, and it will be measured again after four weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Schirmer's test | The Schirmer test score is determined by the length of the moistened area of the strips (using the scale packaged with the strips) and the duration of the measurement in minutes. A score of greater than 10 mm in 5 minutes is accepted as normal. A score of less than 5 mm in 5 minutes indicates a tear deficiency. | Schirmer's test will be measured at baseline, and after four weeks |
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Inclusion Criteria:
Exclusion Criteria:
• Injuries and previous surgical treatment of eyes
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sara Ahmed, lecturer | Contact | 01063998331 | Saramagdy87@cu.edu.eg | |
| Amel Yousef, Professor | Contact | 01222726511 | Amelyousef@pt.cu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Sara Ahmed, lecturer | giza, Egypt, 12511 | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University | Recruiting | Cairo | 11432 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41634440 | Derived | Mohamed Elsayed Saad E, Magdy Ahmed S, Mohamed Yousef A, Shahat Hassan E. Effect of Bioptron light therapy on dryness of eyes in postmenopausal women: a randomized controlled trial. Lasers Med Sci. 2026 Feb 4;41(1):20. doi: 10.1007/s10103-026-04807-6. |
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