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| Name | Class |
|---|---|
| Centre Hospitalier Universitaire de Saint Etienne | OTHER |
| Bicetre Hospital | OTHER |
| University Hospital, Caen | OTHER |
| Central Hospital, Nancy, France |
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Establish the largest possible real-life cohort collecting long-term follow-up of a maximum number of CML patients in order to carry out observational studies: epidemiological, identification of subgroups according to their response to treatment, evaluation of new molecules in real life, therapeutic discontinuations, impact of the evolution of recommendations, etc.
Observational study collecting real-life clinico-biological data from patients with CML. Data are collected prospectively and retrospectively, from diagnosis and throughout the long-term follow-up of CML (follow up continues after treatment stopped).
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| Measure | Description | Time Frame |
|---|---|---|
| Clinical and biological data collection | Aims of the registry are the collection of clinical data to gain further insights about patients's CML treated with ITK's (treatment, prognosis, therapeutical response). | Until death or last follow up (up to 30 years) |
| Measure | Description | Time Frame |
|---|---|---|
| Prognosis score for CML (Sokal, ELTS, Eutos, Hasford) | At diagnosis | |
| BMI with evaluation of weight and height | Until death or last follow up (up to 30 years) | |
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Inclusion Criteria:
Exclusion Criteria:
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Any patient with a diagnose of CML
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lise Laclautre | Contact | 04 73 75 11 95 | promo_interne_drci@chu-clermontferrand.fr |
| Name | Affiliation | Role |
|---|---|---|
| Marc BERGER, MD | University Hospital, Clermont-Ferrand | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CH Annecy Genevois | Recruiting | Annecy | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36040480 | Result | Saugues S, Lambert C, Daguenet E, Ansah HJ, Turhan A, Huguet F, Guerci-Bresler A, Tchirkov A, Hamroun D, Hermet E, Pereira B, Berger MG. Real-world therapeutic response and tyrosine kinase inhibitor discontinuation in chronic phase-chronic myeloid leukemia: data from the French observatory. Ann Hematol. 2022 Oct;101(10):2241-2255. doi: 10.1007/s00277-022-04955-z. Epub 2022 Aug 30. |
| Label | URL |
|---|---|
| Real-world therapeutic response and tyrosine kinase inhibitor discontinuation in chronic phase-chronic myeloid leukaemia: Data from the French observatory | View source |
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| ID | Term |
|---|---|
| D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
| D007938 | Leukemia |
| D007951 | Leukemia, Myeloid |
| D000092122 | Bronchiolitis Obliterans Syndrome |
| D019337 | Hematologic Neoplasms |
| ID | Term |
|---|---|
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D009196 | Myeloproliferative Disorders |
| D001855 | Bone Marrow Diseases |
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| OTHER |
| University Hospital, Toulouse | OTHER |
| CH Annecy Genevois | OTHER |
| Rennes University Hospital | OTHER |
| Hopital Paul Brousse | OTHER |
| Versailles Hospital | OTHER |
| Centre Hospitalier Emile Roux | OTHER |
| University Hospital, Limoges | OTHER |
| Institut Paoli-Calmettes | OTHER |
| Centre Hospitalier de Rochefort | OTHER |
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| Evaluation of major molecular response (MMR) with transcript BCR::ABL in % |
| Until death or last follow up (up to 30 years) |
| Evaluation of molecular response MR4 with transcript BCR::ABL in % | Until death or last follow up (up to 30 years) |
| Evaluation of molecular response MR4.5 with transcript BCR::ABL in % | Until death or last follow up (up to 30 years) |
| Evaluation of molecular response MR5 with transcript BCR::ABL in % | Until death or last follow up (up to 30 years) |
| Evaluation of cytogenetic response | Until death or last follow up (up to 30 years) |
| Evaluation of TKI efficacy based on transcript BCR::ABL in % | Until death or last follow up (up to 30 years) |
| Evaluation of TKI tolerance (adverses events) | Until death or last follow up (up to 30 years) |
| Calcul in month of the duration of maintenance TFR (treatment free remission) after stop TKI for thérapeutic response | Until death or last follow up (up to 30 years) |
| Listing of major medical history of patient's CML | Until death or last follow up (up to 30 years) |
| University Hospital, Caen | Recruiting | Caen | France |
|
| CHU Clemront-Ferrand | Recruiting | Clermont-Ferrand | France |
|
| Centre Hospitalier Emile Roux | Recruiting | Le Puy-en-Velay | France |
|
| University Hospital, Limoges | Recruiting | Limoges | France |
|
| Institut Paoli-Calmettes | Recruiting | Marseille | France |
|
| Centre Hospital, Nancy | Recruiting | Nancy | France |
|
| Bicetre Hospital | Recruiting | Paris | France |
|
| Hopital Paul Brousse | Recruiting | Paris | France |
|
| Rennes University Hospital | Recruiting | Rennes | France |
|
| Centre Hospitalier de Rochefort | Recruiting | Rochefort | France |
|
| Centre Hospitalier Universitaire de Saint Etienne | Recruiting | Saint-Etienne | France |
|
| University Hospital, Toulouse | Recruiting | Toulouse | France |
|
| Versailles Hospital | Recruiting | Versailles | France |
|
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000092124 | Organizing Pneumonia |
| D001989 | Bronchiolitis Obliterans |
| D001988 | Bronchiolitis |
| D001991 | Bronchitis |
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D006086 | Graft vs Host Disease |
| D007154 | Immune System Diseases |
| D009371 | Neoplasms by Site |