Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure

The Impact of Slow, Continuous Infusion of Sodium Chloride or Glucose Solution on Diuresis and Urine Composition During Decongestion of Acute Heart Failure Patients

The aim of the study is to compare the differences in diuretic, natriuretic and clinical response to decongestion in patients receiving different replacement fluid regimens (0.9% sodium chloride vs 5% glucose) in acute heart failure.

Inclusion Criteria:

• patients >18 years old who sign the informed consent
• the primary cause of hospitalization is Acute Heart Failure with a need for intravenous Furosemide
• the start of the study within 24h of hospital admission

Exclusion Criteria:

• need for inotropic support
• end stage renal disease on dialysis
• serum sodium > 148mmol/l or < 130 mmol/l.