Optimizing Open Label Placebo Rationales

Optimizing Open Label Placebo Rationales for Chronic Pain

A 3-arm randomized trial where all chronic pain patients will receive honest placebos, but the information about the placebos will differ between conditions. Outcomes are measured for 21 days and a qualitative survey will be conducted.

Inclusion Criteria:

• chronic pain
• 18 years old
• English speaking
• have a smartphone or computer with video access
• Taking prescription opioids for chronic pain
• the chronic pain is concentrated into the patient's lower back.

Exclusion Criteria:

• suspect an allergy to any placebo ingredient
• problematic substance use
• cancer diagnosis causing pain
• anticipated change in opioid script during the study period.