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Will there be a difference in Pink Esthetic score and soft tissue changes around immediate implants in maxillary esthetic zone following grafting the jumping gap with partially demineralized dentin matrix compared with xenograft?
This study aims to evaluate the soft tissue changes as well as hard tissue changes around immediate implants in maxillary esthetic zone following grafting the jumping gap with partially demineralized dentin matrix in comparison to xenograft.
Because xenogeneic bone is so readily available in substantial quantities, it has been the subject of notable research. However, because they contain organic material from a foreign species, xenogeneic bones are inherently very antigenic.
According to experimental results, PDDM encourages bone regeneration in a manner like autogenous bone. Both cortical bone and autogenous tooth grafts share similar physical and chemical characteristics, including optimal biodegradability, not requiring a separate surgery to harvest the graft and space maintenance capabilities. PDDM is a valuable comparator to autogenous bone in ARP and around dental implants in guided bone regeneration procedures
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Partially demineralized dentin matrix graft | Experimental |
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| xenograft | Active Comparator |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Immediate implant | Procedure |
grafting material either experimental or control will be used to graft jumping gap. |
| Measure | Description | Time Frame |
|---|---|---|
| Pink esthetic score | a fourteen point scale to evaluate pink esthetics. The pink esthetic score (PES) estimates the esthetic results of soft tissue surrounding the implant with regarding 7 points : mesial, distal papilla, soft tissue margin, soft tissue contour, alveolar process, colour, texture. the score of zero will be lowest and two will be the highest for each of the seven points with zero being the lowest and 14 being the highest. | twelve months after final restoration |
| Measure | Description | Time Frame |
|---|---|---|
| Vertical and horizontal radiographic changes in bone dimensions | cone beam CT will be used to detect vertical and horizontal changes | immediate post operative and twelve months after final restoration |
| Midfacial mucosal alteration |
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Inclusion Criteria:
Exclusion criteria
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mihad Ibrahim, M.Sc | Contact | (+20)1008551124 | mihad.ibrahim@dentistry.cu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Manal Hosny Mostafa, Professor | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Oral and Dental Medicine- Cairo University | Cairo | Cairo Governorate | 35855 | Egypt |
baseline data and follow up measurements will be shared while keeping patients' identity protected.
till publication
public
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| ID | Term |
|---|---|
| D057893 | Immediate Dental Implant Loading |
| ID | Term |
|---|---|
| D003758 | Dental Implantation, Endosseous |
| D003757 | Dental Implantation |
| D013516 | Oral Surgical Procedures, Preprosthetic |
| D019647 | Oral Surgical Procedures |
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The two groups will be equally prepared for both surgical procedures. Then the decision of which group will receive (PDDM), and which will receive xenograft will be taken according to the randomized numbers placed in opaque sealed envelopes. The number will be picked by the supervisor.
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rubber base impressions taken before the surgical procedure and 12 months after implant restoration. Then, casts were poured with type IV die stone and optically scanned. The obtained models were compared by digital superimposition in a matching software to measure the vertical alterations of the buccal peri-implant soft tissue.
| preoperative and twelve months after final restoration |
| Patient satisfaction | a twelve point questionnaire to evaluate patient satisfaction | one year after final restoration |
| D013514 | Surgical Procedures, Operative |
| D019919 | Prosthesis Implantation |
| D003813 | Dentistry |
| D011476 | Prosthodontics |