Complications Related to Vascular Access Devices in Home Parenteral Nutrition Patients

Venous Thromboembolism and Infections Associated With Three Vascular Access Devices in Home Parenteral Nutrition : a Prospective Cohort Study

Central vascular access devices are required for home parenteral nutrition (HPN). There is few data available concerning their complications in adult HPN patients, and the potential link between venous thromboembolism and catheter infection is not well established.

The aim of this prospective cohort study is to compare the incidence rate of catheter related complications among 3 types of central vascular access: peripherally inserted central catheters; tunneled catheters and port-a-cath devices, in adults patients on HPN; describe the risk factors, and identify a potential link between venous thromboembolism and infection.

More than 300 patients will be consecutively enrolled and followed up from the time of catheter insertion until its removal. Venous complication (identify by an ultrasound examination if deep vein thrombosis is suspected), infection related to catheter and mechanical complications will be analyzed. The incidence of complications will be expressed per 1000 catheters-day and or as a percentage of total catheter.

Inclusion Criteria:

• adult patients
• having a catheter insertion during the study periode
• at the unit of vascular access of Lyon Sud Hospital
• for parenteral nutrition
• from July 1st, 2017 to June 30, 2020

Exclusion Criteria:

• catheter inserted in intensive care unit
• for other treatment (chemotherapy, antibiotic)