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| Name | Class |
|---|---|
| Chonnam National University Hospital | OTHER |
| Sejong General Hospital | OTHER |
| Keimyung University Dongsan Medical Center | OTHER |
| Korea University Anam Hospital |
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In this study, the investigators analyze the clinical characteristics and prognosis of patients with acute myocarditis in South Korea
Acute myocarditis refers to a condition in which inflammatory cells infiltrate the heart muscle due to various causes. Until now, there is no clear treatment method for myocarditis itself, and when myocardial function deteriorates or arrhythmia occurs due to myocarditis, it is common to wait for natural recovery while performing general supportive treatment for heart failure.
Through this study, the investigators analyze the factors contributing to the long-term prognosis, myocardial recovery rate, and clinical course of myocarditis. And, the investigators plan to establish an appropriate treatment strategy necessary to increase the survival rate of patients with myocarditis.
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| Measure | Description | Time Frame |
|---|---|---|
| Rate of In hospital mortality | In hospital death by any cause | through study completion, an average of 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of all-cause mortality | Death by any cause during follow-up | through study completion, an average of 1 year |
| Requirement of cardiac replacement therapy | Left ventricular assist device insertion or heart transplantation during follow-up |
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Inclusion Criteria:
Exclusion Criteria:
● Coronary artery disease
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Patients diagnosed with acute myocarditis at 6 domestic hospitals in South Korea from January 2004 to December 2021
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| Name | Affiliation | Role |
|---|---|---|
| Jeong Hoon Yang | Samsung Medical Center | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samsung Medical Center | Seoul | 06351 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40628676 | Derived | Hong D, Bak M, Park H, Kim HY, Lee S, Kim IC, Hyun J, Kim SR, Kim MN, Kim KH, Yang JH. Association Between Vasoactive Inotropic Score and Clinical Outcomes in Patients With Fulminant Myocarditis. Korean Circ J. 2025 Oct;55(10):938-951. doi: 10.4070/kcj.2024.0445. Epub 2025 May 28. | |
| 39805629 | Derived | Hyun J, Pack D, Bak M, Park H, Kim HY, Lee S, Kim IC, Kim SR, Kim MN, Kim KH, Lee SE, Yang JH. Clinical Characteristics and Outcomes of Acute Myocarditis: An Analysis of Korean Multicenter Registry. Korean Circ J. 2025 May;55(5):410-422. doi: 10.4070/kcj.2024.0229. Epub 2024 Dec 10. |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Jul 3, 2023 | Jul 3, 2023 | Prot_SAP_000.pdf |
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| OTHER |
| Asan Medical Center | OTHER |
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| through study completion, an average of 1 year |
| Rates of Re-hospitalization due to any cause | Re-hospitalization due to any cause during follow-up | through study completion, an average of 1 year |
| 38936469 | Derived | Bak M, Hyun J, Park H, Kim HY, Lee S, Kim IC, Kim SR, Kim MN, Kim KH, Yang JH. Early unloading and clinical outcomes in patients with fulminant myocarditis undergoing VA-ECMO: results of a multicenter retrospective study. Rev Esp Cardiol (Engl Ed). 2025 Mar;78(3):176-184. doi: 10.1016/j.rec.2024.06.004. Epub 2024 Jun 25. English, Spanish. |