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| Name | Class |
|---|---|
| EBPracticenet | UNKNOWN |
| Fonds National de la Recherche Scientifique | OTHER |
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The goal of this feasibility study is to evaluate the feasibility of a complex intervention towards benzodiazepines and Z-drugs deprescribing in older adults living in the Belgian nursing home setting.
The main questions it aims to answer are:
Participants will benefit from a complex intervention implemented at the level of the nursing home, encompassing process and goals setting, healthcare providers education, environmental adaptations, audit and feedback on benzodiazepines use, use of educational leaflet with residents and relatives, and multidisciplinary work.
Researchers will compare this intervention to usual care, to see if the intervention is feasible, and to gather first data on intervention effectiveness in benzodiazepines deprescriping.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| END-IT intervention for nursing homes | Experimental | This complex intervention, implemented at the level of the nursing home, encompasses process and goals setting, education for healthcare providers, environmental adaptations, audit and feedback on benzodiazepine use, use of an educational leaflet for residents and relatives, and multidisciplinary work. |
|
| Control | No Intervention | Usual care. Nursing homes allocated to this study arm will access intervention material at the end of the study. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| END-IT intervention for nursing homes | Other | Complex intervention, as described in the arm/group descriptions |
|
| Measure | Description | Time Frame |
|---|---|---|
| Nursing homes' adherence to the intervention | has the intervention been implemented as intended, e.g. global number of implemented intervention components | Assessed at 6 months |
| Healthcare providers responsiveness to the intervention | has far did they respond to the intervention, and how far have them been engaged by the intervention, e.g level of attendance to education session for healthcare providers | Assessed at 6 months |
| nursing home residents' responsiveness to the intervention | has far did they respond to the intervention, and how far have them been engaged by the intervention | Assessed at 6 months |
| Feasibility of the recruitment process | The feasibility of the recruitment will be assessed through the ratio between included residents and residents contacted for participation. | At 6 months |
| Feasibility of the data collection process | Data collection process will be assessed through the quality of collected data (rate of missing data) | At 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Contextual factors at the level of of the nursing home | Use of a questionnaire to assess factors that could explain potential differences in intervention implementation between nursing homes | Baseline |
| Contextual factors at the level of the nursing home resident |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Perrine Evrard, MPharm | Contact | +3227647236 | perrine.evrard@uclouvain.be |
| Name | Affiliation | Role |
|---|---|---|
| Anne Spinewine, PhD | UCLouvain / Louvain Drug Research Institute / Clinical pharmacy research group | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UCLouvain | Recruiting | Woluwe-Saint-Lambert | 1200 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39438099 | Derived | Evrard P, Chevallereau T, Aikpitanyi J, Petein C, Tubeuf S, Henrard S, Spinewine A. Feasibility of a theory-based intervention towards benzodiazepine deprescribing in Belgian nursing homes: protocol of the END-IT NH cluster-randomised controlled trial. BMJ Open. 2024 Oct 22;14(10):e085435. doi: 10.1136/bmjopen-2024-085435. |
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Only publishable project data relating to the main analysis and research output will be shared on a data repository after an embargo period of two years after June 2024. All relevant documentation necessary to facilitate data re-use will be shared along with the datasets.
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| ID | Term |
|---|---|
| D009735 | Nursing Homes |
| ID | Term |
|---|---|
| D012112 | Residential Facilities |
| D006268 | Health Facilities |
| D005159 | Health Care Facilities Workforce and Services |
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Use of a questionnaire to assess factors that could explain potential differences in intervention implementation between nursing home residents |
| Baseline |
| Intervention mechanisms of impact | Use of a questionnaire to assess intervention mechanisms of impact, in relation with how the intervention is supposed to have its impact | At baseline |
| Intervention mechanisms of impact | Use of a questionnaire to assess intervention mechanisms of impact, in relation with how the intervention is supposed to have its impact. | At 3 months |
| Intervention mechanisms of impact | Use of a questionnaire to assess intervention mechanisms of impact, in relation with how the intervention is supposed to have its impact. | At 6 months |
| Exploratory benzodiazepine deprescribing rate analysis | Defined as either a complete benzodiazepine/Z-drug cessation, or a dose reduction | At 3 months |
| Exploratory benzodiazepine deprescribing rate analysis | Defined as either a complete benzodiazepine/Z-drug cessation, or a dose reduction | At 6 months |