Dentin hypersensitivity (DH) is a common clinical problem frequently seen in dental patients. According to Splieth et al., the prevalence of dentin hypersensitivity is 3-98% in adult population.DH is described as a short, sharp pain or discomfort that responses to certain stimuli, typically thermal, tactile, osmotic or chemical, due to exposed dentinal surface which can be explained by the hydrodynamic theory.

The laser is a narrow, focused beam of light emitted to vaporise, fuse, melt, or seal dentinal tubules using laser heat to induce hydroxyapatite crystals for recrystallisation of the mineral component of dentine. The obliteration of dentinal tubules is caused by heat generated by laser beam which inhibits the transmission of the stimulus in the dentinal tubules.

Grape seed extract contains proanthocyanidins (PA) which is able to bind to proline-rich proteins, like collagen, and contributes in enzyme proline hydroxylase activity that is essential for the biosynthesis of collagen in the dentin. The cross-linking action of collagen fibrils in dentin also able to prevent mineral loss.

Inclusion Criteria:

• Patients with at least three sensitive tooth by gingival recession or tooth wear >2 scores on the VAS scale.
• Tooth wear index score <3 (Smith and Knight tooth wear index)
• Systemically healthy patient.
• 20-50 years of age.

Exclusion Criteria:

• Teeth with caries, cracked teeth, mobile teeth and pulpitis.
• Deep periodontal pockets (probing depth >6 mm), periodontal surgery within the previous 3 months.
• Recent desensitizing therapy
• systemic diseases and gastric diseases (GERD)
• Allergy to active ingredients.