Effects of Antibiotic Prophylaxis on the Healing Parameters Following Surgical Crown Lengthening

Effects of Pre-operative Antibiotics on the Wound Healing Following Clinical Crown Lengthening Surgery

The goal of this clinical trial is to test the effects of prophylactic antibiotics in healthy individuals who are in need of surgical crown lengthening. The main question it aims to answer is if single dose antibiotics prior to surgical crown lengthening has any effects on the healing outcomes.

Participants will be asked to take either

• 2 g of amoxicillin + clavulanate, or
• placebo, one hour prior to surgery and without knowing what medicine they took.

Researchers will compare the wound healing and self-reported outcomes of the antibiotics group and placebo group.

Inclusion Criteria:

• in need of surgical crown lengthening operation in one/two teeth

Exclusion Criteria:

• systemic diseases which may affect periodontal tissues and/or healing process such as diabetes mellitus
• antibiotic or anti-inflammatory drug use in the last 3 months
• pregnancy/lactation
• chronic steroid, immunosuppressant or NSAD use
• age <18 years
• positive bleeding on probing at the surgical site and/or active periodontal disease
• <2 mm keratinized mucosa at the surgical site following surgery (estimated surgical outcome before the operation)
• Miller 2 or 3 tooth mobility
• penicillin allergy
• unwilling to participate