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| Name | Class |
|---|---|
| Yiwu Central Hospital | OTHER |
| Jinhua Municipal Central Hospital | OTHER |
| Jinhua People's Hospital | OTHER |
| Lanxi People's Hospital |
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The goal of this clinical trial is to test the cooling effect of cooling blanket in patients with heat stroke. The main questions it aims to answer are:
Participants will accept the cooling blanket or non-cooling blanket according to the randomization group.
Researchers will compare cooling rate and outcomes to see if the cooling blanket can accelerate the cooling speed and improve the prognosis of patients in heat stroke.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| non-cooling blanket group | Experimental | Cooling body temperature by: control the temperature of the emergency room to 20-24℃, 4℃ fluid infusion, ice packs, evaporation, convection, etc. |
|
| Cooling blanket group | Active Comparator | On the basis of the cooling methods of non-cooling blanket group, combine the cooling blanket to cool down. The cooling blanket is required to be activated within 30min after admission. The blanket temperature will be set at 4-10℃, and the target body temperature is 38℃. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cooling blanket | Device | On the basis of the cooling methods of non-cooling blanket group, combine the cooling blanket to cool down. The cooling blanket is required to be activated within 30min after admission. The blanket temperature will be set at 4-10℃, and the target body temperature is 38℃. |
| Measure | Description | Time Frame |
|---|---|---|
| 0.5-hour temperature reduction | Calculated as the difference between initial core temperature and core temperature at 0.5 hours after admission. | 0.5 hours |
| Body temperature of 0.5 hours | Body temperature of 0.5 hours referred to the temperature value obtained 5 min before and after 0.5 hour. | 0.5 hours after admission to emergency department |
| Measure | Description | Time Frame |
|---|---|---|
| Body temperature of 2 hours | Body temperature of 2 hours referred to the temperature value obtained 20 min before and after 2 hours. | 2 hours |
| incidence of organ damage | number of participants with organ damage, including but not limited to brain, lung, heart, kidney, liver, and coagulation function |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xiuqin Feng | Contact | +8613757119151 | fengxiuqin@zju.edu.cn | |
| Lan Chen | Contact | +8613819987120 | jhchenlan2003@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Lan Chen | Second Affiliated Hospital, School of Medicine, Zhejiang University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Yongkang No.1 People's Hospital | Recruiting | Guli | Zhejiang | 321300 | China |
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| OTHER |
| Yongkang No.1 People' s Hospital | UNKNOWN |
| Dongyang People's Hospital | OTHER |
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|
| non-cooling blanket | Device | Patients do not receive cooling blanket according to randomization. Cooling body temperature by: control the temperature of the emergency room to 20-24℃, 4℃ fluid infusion, ice packs, evaporation, convection,etc. |
|
| up to 90 days |
| length of ICU stay | The length patient stay at ICU | up to 90 days |
| in-hospital mortality | number of participants dead in-hospital | up to 90 days |
| Yiwu Central Hospital | Recruiting | Yiwu | Zhejiang | China |
|
| Dongyang People's Hospital | Recruiting | Dongyang | China |
|
| The Second Affiliated Hospital of Zhejiang University School of Medicine | Recruiting | Hangzhou | 310000 | China |
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| Jinhua Municipal Central Hospital | Recruiting | Jinhua | China |
|
| Jinhua People's Hospital | Recruiting | Jinhua | China |
|
| Lanxi People's Hospital | Recruiting | Lanxi | China |
|
| ID | Term |
|---|---|
| D018883 | Heat Stroke |
| ID | Term |
|---|---|
| D018882 | Heat Stress Disorders |
| D014947 | Wounds and Injuries |
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