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Brief Summary:
Participants with rheumatoid arthritis with recommendation to physiotherapy.
Created 2 study groups:
Pulsed magnetic field give better effects then static magnetic field.
Participants with rheumatoid arthritis with recommendation to physiotherapy. All participants have dysfunction and pain of hand. Before entering the study, all patients were examined by a rheumatologist, who determined the degree of radiological and functional changes and measured blood pressure. Patients with II° and III° of radiological and functional changes were qualified for the study. All the patients gave their informed consent to participate in the study. The examination included an overall assessment of functional status. Patients were examined immediately before and after the intervention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Kinesiotherapy with Static Magnetic Field | Experimental | Patients have kinesiotherapy of hand and static magnetic field. All patients without steroid anti-inflammatory drugs. |
|
| Kinesiotherapy with low-frequency pulsed magnetic field | Experimental | Patients have kinesiotherapy of hand and low-frequency pulsed magnetic field. All patients without steroid anti-inflammatory drugs. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Kinesiotherapy with magnetotherapy | Other | Individual kinesiotherapy. Parameters of magnetic field: 7 mT, f= 10-20 Hz, type of impulse: bipolar, rectangular pulse |
|
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analogue Scale | Pain severity rating scale. only one value. Minimum value is 0, maximum value is 10. The best is 0, the worst is 10. | Change from baseline VAS value immediately after therapy. |
| Health Assesment Questionaire | Subjective assesment of level of disability. Value of each of 8 subsections: minimum value 0, maximum value 3. total score is averaged. The best total score is 0, the worst is 3. | Change from baseline HAQ-20 value immediately after therapy. |
| Range of motion | Computerized measurement of the range of motion of the joints of the hand [mm]. A higher score value meant a greater range of motions. | Change from baseline range of motion value immediately after therapy. |
| Displacement hand volume measurement | Measurement of hand volume using the displacement method [mm3]. The higher score means less swelling. | Change from baseline volume value immediately after therapy. |
| Persistence time of morning stiffness | Patient's subjective assessment of the duration of morning stiffness [min]. The longer durations means more hand dysfunction. | Change from baseline time of morning stiffness value immediately after therapy. |
| Severity of morning stiffness | Assessing the severity of morning stiffness using a 100-point scale. The higher score means a greater severity of morning stiffness. | Change from baseline time of severity of morning stiffness value immediately after therapy. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jolanta Zwolinska, PhD | University of Rzeszow | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Laboratorium Czynników Fizykalnych w Rehabilitacji w Przyrodniczo-Medycznym Centrum Badań Innowacyjnych Uniwersytetu Rzeszowskiego | Rzeszów | Podkarpackie Voivodeship | 35-310 Rzeszów | Poland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28842627 | Background | Parate D, Franco-Obregon A, Frohlich J, Beyer C, Abbas AA, Kamarul T, Hui JHP, Yang Z. Enhancement of mesenchymal stem cell chondrogenesis with short-term low intensity pulsed electromagnetic fields. Sci Rep. 2017 Aug 25;7(1):9421. doi: 10.1038/s41598-017-09892-w. | |
| 35586276 | Result | Tong J, Chen Z, Sun G, Zhou J, Zeng Y, Zhong P, Deng C, Chen X, Liu L, Wang S, Chen J, Liao Y. The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis. Pain Res Manag. 2022 May 9;2022:9939891. doi: 10.1155/2022/9939891. eCollection 2022. |
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| ID | Term |
|---|---|
| D001172 | Arthritis, Rheumatoid |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| ID | Term |
|---|---|
| D055909 | Magnetic Field Therapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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Assessor evaluating the patients' condition had no knowledge of the outcome of randomization of patients to the study groups.
|
| 34210094 | Result | Chen Y, Aspera-Werz RH, Menger MM, Falldorf K, Ronniger M, Stacke C, Histing T, Nussler AK, Ehnert S. Exposure to 16 Hz Pulsed Electromagnetic Fields Protect the Structural Integrity of Primary Cilia and Associated TGF-beta Signaling in Osteoprogenitor Cells Harmed by Cigarette Smoke. Int J Mol Sci. 2021 Jun 29;22(13):7036. doi: 10.3390/ijms22137036. |
| 25955771 | Result | Dundar U, Asik G, Ulasli AM, Sinici S, Yaman F, Solak O, Toktas H, Eroglu S. Assessment of pulsed electromagnetic field therapy with Serum YKL-40 and ultrasonography in patients with knee osteoarthritis. Int J Rheum Dis. 2016 Mar;19(3):287-93. doi: 10.1111/1756-185X.12565. Epub 2015 May 8. |
| 30552258 | Result | Wu Z, Ding X, Lei G, Zeng C, Wei J, Li J, Li H, Yang T, Cui Y, Xiong Y, Wang Y, Xie D. Efficacy and safety of the pulsed electromagnetic field in osteoarthritis: a meta-analysis. BMJ Open. 2018 Dec 14;8(12):e022879. doi: 10.1136/bmjopen-2018-022879. |
| D003240 |
| Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |