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The goal of this study is to compare the success rate of subcutaneously infiltrated nicardipine to normal saline in radial artery cannulation
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nicardipine | Experimental | Using nicardipine 0.5 mg(0.5ml) subcutaneously infiltrated by ultrasound before redial artery cannulation. |
|
| Normal saline | Placebo Comparator | Using normal saline 0.5ml subcutaneously infiltrated by ultrasound before redial artery cannulation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nicardipine | Drug | Subcutaneous infiltrate drug at puncture site by ultrasound-guided |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Success rate of radial artery cannulation since first skin puncture | Success rate of radial artery cannulation since first skin puncture | 10 minute from puncture at skin |
| Measure | Description | Time Frame |
|---|---|---|
| radial artery diameter | Pre-induction radial artery diameter, post-induction radial artery diameter, radial artery diameter after subcutaneous infiltration at 0,1,2 and 3 minute | Pre-induction to 3 minute after subcutaneous infiltration |
| Time from first skin puncture to success cannulation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Phuriphon Songarj, MD | Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anesthesiology Department | Bangkok | 10700 | Thailand |
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| ID | Term |
|---|---|
| D009529 | Nicardipine |
| D000077330 | Saline Solution |
| ID | Term |
|---|---|
| D004095 | Dihydropyridines |
| D011725 | Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| Normal saline |
| Other |
Subcutaneous infiltrate NSS at puncture site by ultrasound-guided |
|
Time from first skin puncture to present of arterial wave form, assessed less than 10 minutes |
| 10 minutes |
| D000077324 |
| Crystalloid Solutions |
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |