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Study population will consist of HRD+ (BRCAm +/- positive genomic instability score according to used test system) OC with available medical history. It is estimated that approximately 400 patients will be enrolled in approximately 25 sites. Demographic and clinical characteristics, treatment approaches and outcomes in HRD+ patients with high-grade epithelial ovarian, primary peritoneal, and/or fallopian tube cancer will be collected at baseline and on prospective visits.
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| Measure | Description | Time Frame |
|---|---|---|
| To describe the demographic and clinical characteristics of the patient population with HRD-positive OC (HRD+ BRCAwt and HRD+ BRCAm) | Demographic and baseline clinical characteristics will be summarized descriptively for the entire cohort of eligible patients. | 18 months |
| Measure | Description | Time Frame |
|---|---|---|
| To describe diagnostic and primary treatment approaches (surgery, first line chemotherapy+/-bevacizumab) of HRD+ with high-grade, epithelial ovarian, primary peritoneal, and/or fallopian tube cancer in routine practice | population and the maintenance regimens initiated after the primary OC therapy . | 18 months |
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Inclusion Criteria:
Exclusion Criteria:
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Study population will consist of HRD+ (BRCAm +/- positive genomic instability score according to used test system) OC with available medical history. It is estimated that approximately 400 patients will be enrolled in approximately 25 sites. Demographic and clinical characteristics, treatment approaches and outcomes in HRD+ patients with high-grade epithelial ovarian, primary peritoneal, and/or fallopian tube cancer will be collected at baseline and on prospective visits.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Research Site | Arkhangelsk | Russia | ||||
| Research Site |
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| Label | URL |
|---|---|
| Redacted CSR synopsis | View source |
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| To describe first-line maintenance treatment approaches |
population and the maintenance regimens initiated after the primary OC therapy . |
| 18 months |
| Barnaul |
| Russia |
| Research Site | Chelyabinsk | Russia |
| Research Site | Grozny | Russia |
| Research Site | Irkutsk | Russia |
| Research Site | Izhevsk | Russia |
| Research Site | Kaliningrad | Russia |
| Research Site | Kaluga | Russia |
| Research Site | Krasnodar | Russia |
| Research Site | Krasnoyarsk | Russia |
| Research Site | Lyubertcy | Russia |
| Research Site | Moscow | Russia |
| Research Site | N.Novgorod | Russia |
| Research Site | Nal'chik | Russia |
| Research Site | Novosibirsk | Russia |
| Research Site | Omsk | Russia |
| Research Site | Saint Petersburg | Russia |
| Research Site | Saratov | Russia |
| Research Site | Sochi | Russia |
| Research Site | Tomsk | Russia |
| Research Site | Ufa | Russia |
| Research Site | Vladivostok | Russia |
| Research Site | Yakutiya | Russia |
| Research Site | Yaroslavl | Russia |
| ID | Term |
|---|---|
| D010051 | Ovarian Neoplasms |
| ID | Term |
|---|---|
| D004701 | Endocrine Gland Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D010049 | Ovarian Diseases |
| D000291 | Adnexal Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D005833 | Genital Neoplasms, Female |
| D014565 | Urogenital Neoplasms |
| D000091662 | Genital Diseases |
| D004700 | Endocrine System Diseases |
| D006058 | Gonadal Disorders |
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