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| Name | Class |
|---|---|
| Mỹ Đức Hospital | OTHER |
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In the past three decades, obesity has emerged insurmountably, not only in affluent nations but also in many low- and middle-income countries worldwide. It has been linked to various non-communicable diseases, including hypertension, coronary heart disease, diabetes mellitus, dyslipidemia, stroke, colorectal cancer, and many other chronic conditions, such as musculoskeletal disorders, putting tremendous pressure on healthcare systems and the socio-economy. The Asia and Pacific region harbors the highest absolute number of people with overweight and obese, amounting to approximately 1 billion. In Southeast Asia, the prevalence of overweight and obesity increased by almost 40% between 1990 and 2013. Although Vietnam has the lowest percentage of obese adults in the region (about 3.6%), we experienced a 38% increase in the number of obese people between 2010-2014, much higher than that in the University Kingdom and the United States (10% and 8% correspondingly). However, the problem is underestimated by not only healthcare professionals but also patients with obesity. These alarms underscore the necessity of implementing a comprehensive assessment and more focused and practical strategies for addressing obesity in Vietnam, where data has been limited. Therefore, our research has two arms: (1) characterization of patients with obesity to identify those at the highest risks for obesity complications, and (2) understating the attitudes and perceptions of people living with obesity to gain insights into the psychological factors associated with obesity. This research will be a foundation for further research on obesity in Vietnam and Southeast Asia.
All Vietnamese, aged 18-65, diagnosed with obesity defined by BMI ≥ 25 kg/m2 as per Asia-Pacific Guidelines for Obesity, present at University Medical Center Ho Chi Minh City and My Duc General Hospital outpatient clinics, will be enrolled to the study. The patients will have:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| OPT OBESE | Vietnamese patients with obesity present at outpatient clinics of University Medical Center Ho Chi Minh City and My Duc General Hospital |
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| Measure | Description | Time Frame |
|---|---|---|
| Weight measurement | Using standardized weight scale (ISO 9001:2015) | At baseline |
| Height measurement | Using a professional medical HM200P Portable Height Stadiometer | At baseline |
| Body Mass Index | Weight in kilograms divided by height in meters squared | At baseline |
| Waist circumference | To be measured at the approximate midpoint between the lower margin of the last palpable rib and the top of the iliac crest | At baseline |
| Hip circumference | To be measured around the widest portion of the buttocks. | At baseline |
| Blood pressure | Systolic and diastolic pressure measurements will be taken using a standardized sphygmomanometer. | At baseline |
| Fasting plasma glucose | Fasting plasma glucose (mmol/L) concentrations in serum | At baseline |
| HDL cholesterol | HDL cholesterol (mmol/L) concentrations in serum | At baseline |
| Measure | Description | Time Frame |
|---|---|---|
| The relationship between the severity of obesity to anthropometric parameters | The correlation between the severity of obesity to anthropometric parameters (waist circumference, hip circumference, weight, height, and BMI) will be evaluated. | At baseline |
| The relationship between the severity of obesity to biochemical parameters |
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Inclusion Criteria:
Exclusion Criteria:
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All Vietnamese, aged 18-65, diagnosed with obesity defined by BMI ≥ 25 kg/m2 as per Asia-Pacific Guidelines for Obesity, present at University Medical Center Ho Chi Minh City and My Duc General Hospital outpatient clinics will be enrolled to the study.
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| Name | Affiliation | Role |
|---|---|---|
| Nam Q Tran, MD, PhD | University Medical Center Ho Chi Minh City (UMC) | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| My Duc General Hospital | Ho Chi Minh City | 70000 | Vietnam | |||
| University Medical Center Ho Chi Minh City (Umc) |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Jun 12, 2023 | Jun 13, 2023 | Prot_000.pdf |
| ICF | No | No | Yes | Informed Consent Form | Jun 12, 2023 | Jun 13, 2023 | ICF_001.pdf |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| LDL cholesterol |
LDL cholesterol (mmol/L) concentrations in serum |
| At baseline |
| Triglycerides | Triglycerides (mmol/L) concentrations in serum | At baseline |
| Total cholesterol | Total cholesterol (mmol/L) concentrations in serum | At baseline |
| Body composition change | Body fat mass (% BFM), body fat percentage (%BF), muscle mass, skeletal muscle mass (% SMM) and visceral fat rating will be evaluated to assess body composition change. Measurements will be assessed using a Electrical bioimpedance (BIA) | At baseline |
| Risk of depression score | Risk of depression will be assessed using PHQ-9 (Patient Health Questionnaire-9). It is scored on a 27-point scale. Those with a PHQ-9 score less than five is considered at no risk of depression, and those with a PHQ-9 score equal to or more than 5 are at risk of depression. | At baseline |
The correlation between the severity of obesity to biochemical parameters (fasting plasma glucose, LDL cholesterol, HDL cholesterol, triglycerides, and total cholesterol) will be evaluated. |
| At baseline |
| The relationship between the severity of obesity to body composition | The correlation between the severity of obesity to body composition (body fat mass (% BFM), body fat percentage (%BF), muscle mass, skeletal muscle mass (% SMM) and visceral fat rating) will be evaluated. | At baseline |
| The relationship between the severity of obesity to risk of depression | The correlation between the severity of obesity to risk of depression (PHQ-9 score) will be evaluated. | At baseline |
| Ho Chi Minh City |
| 70000 |
| Vietnam |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |