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| ID | Type | Description | Link |
|---|---|---|---|
| I8H-MC-BDDF | Other Identifier | Eli Lilly and Company |
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The main purpose of this study is to compare the two formulations of LY3209590 in healthy participants. Study participants will be administered each formulation at separate study visits. Blood samples will be taken to compare how the body handles study drugs. The information about any adverse effects experienced will be collected and the tolerability of LY3209590 will also be evaluated.
Screening is required within 28 days prior to enrolment. For each participant, the total duration of the clinical trial will be about 184 days including screening.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| LY3209590 (Formulation 1) | Experimental | Single dose of LY3209590 as formulation 1 administered subcutaneously (SC). |
|
| LY3209590 (Formulation 2) | Experimental | Single dose of LY3209590 as formulation 2 administered SC. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| LY3209590 (Formulation 1) | Drug | Administered SC. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve from Time Zero to the Last Time Point (AUC[0-tlast]) of LY3209590 | PK: AUC(0-tlast) of LY3209590 | Predose up to 65 days post dose |
| PK: Area Under the Plasma Concentration Versus Time Curve From Zero to Infinity (AUC[0-∞]) of LY3209590 | PK: AUC(0-∞) of LY3209590 | Predose up to 65 days post dose |
| PK: Maximum Observed Concentration (Cmax) of LY3209590 | PK: Cmax of LY3209590 | Predose up to 65 days post dose |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST) | Eli Lilly and Company | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lilly Centre for Clinical Pharmacology | Singapore | 138623 | Singapore |
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| LY3209590 (Formulation 2) |
| Drug |
Administered SC. |
|