Due to lack of funding, we have been unable to continue research activities. The future related to funding support does not look promising, therefore it is best to discontinue this project.

An observational study following up with trigeminal neuralgia patients to understand their comorbid facial pain condition, specifically temporomandibular disorder.

This multi-center prospective observational cohort study aims to investigate the prevalence of comorbid Temporomandibular disorders (TMD) among trigeminal neuralgia (TN) patients. Trigeminal neuralgia patients with active TN status from three clinical sites (University of Minnesota, School of Dentistry, Orofacial Pain Clinic; Mhealth Fairview, Clinical Surgical Center, Neurosurgery Clinic; John Hopkins University, Anesthesiology, and Critical Care Clinic) could enroll in this study voluntary. All the patients will be evaluated by a provider using standard clinical assessment for TN and TMD, along with validated RedCap questionnaires for TN and TMD diagnosis, and be followed up every six months for 1-2 years.

Inclusion Criteria:

• Patients visited the three clinical sites for facial pain
• Patients diagnosed with trigeminal neuralgia
• Has active pain symptoms in the past 30 days

Exclusion Criteria:

• Non-English speakers
• Patients with psychiatric disorders that might alter pain perception
• Adults lack the capacity to provide informed consent.
• Persons under the age of 18.
• All vulnerable populations.

Patients that visited three clinical centers in the study who sought care for their facial pain were diagnosed with trigeminal neuralgia, with active symptoms in the past 30 days.

The final results will be shared with all the participants as a summary.

By end of 2024