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| ID | Type | Description | Link |
|---|---|---|---|
| PRO00028349 | Other Identifier | UF | |
| 5U01NS119562 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| Augusta University | OTHER |
| Albany Medical College | OTHER |
| Beth Israel Deaconess Medical Center | OTHER |
| Duke University |
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The purpose of this study is to test the performance of the AID-P across 21 sites in the Parkinson Study Group. Each site will perform imaging, clinical scales, diagnosis, and will upload the data to the web-based software tool. The clinical diagnosis will be blinded to the diagnostic algorithm and the imaging diagnosis will be compared to the movement disorders trained neurologist diagnosis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Parkinson's disease | Clinically diagnosed Parkinson's disease |
| |
| Multiple System Atrophy, Parkinsonian variant | Clinically diagnosed Multiple System Atrophy, Parkinsonian variant |
| |
| Progressive Supranuclear Palsy | Clinically diagnosed Progressive Supranuclear Palsy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| AIDP | Diagnostic Test | Machine learning algorithm of imaging data |
|
| Measure | Description | Time Frame |
|---|---|---|
| Predicted diagnosis accuracy | utilizing the automated imaging differentiation of Parkinsonism (AIDP) tool to predict diagnosis compared to the expertise of two movement disorder specialists | 12-18 months |
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Inclusion Criteria:
Exclusion Criteria:
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Adults between the ages of 40 and 80 who meet one of the three diagnoses: PD, MSAp, or PSP
*As of 11/9/23, we have filled the cohorts for both PD and PSP patients. We are only enrolling MSAp patients at this time.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | United States | ||
| University of California San Diego |
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| OTHER |
| Johns Hopkins University | OTHER |
| Massachusetts General Hospital | OTHER |
| Northwestern University | OTHER |
| Ottawa Hospital Research Institute | OTHER |
| Penn State University | OTHER |
| University of Alabama at Birmingham | OTHER |
| University of California, San Diego | OTHER |
| University of California, San Francisco | OTHER |
| University of Chicago | OTHER |
| University of Michigan | OTHER |
| University of Minnesota | OTHER |
| University of South Florida | OTHER |
| Centre for Addiction and Mental Health | OTHER |
| Wake Forest University | OTHER |
| Washington University School of Medicine | OTHER |
| University of Kentucky | OTHER |
| National Institute of Neurological Disorders and Stroke (NINDS) | NIH |
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| La Jolla |
| California |
| 92037 |
| United States |
| University of California San Francisco | San Francisco | California | 94158 | United States |
| University of Florida | Gainesville | Florida | 32611 | United States |
| University of South Florida | Tampa | Florida | 33613 | United States |
| Augusta University | Augusta | Georgia | 30912 | United States |
| Northwestern University | Chicago | Illinois | 60611 | United States |
| University of Chicago | Chicago | Illinois | 60637 | United States |
| University of Kentucky | Lexington | Kentucky | 40536 | United States |
| Johns Hopkins University | Lutherville | Maryland | 21093 | United States |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | United States |
| Massachusetts General Hospital | Charlestown | Massachusetts | 02129 | United States |
| University of Michigan | Ann Arbor | Michigan | 48106 | United States |
| University of Minnesota | Minneapolis | Minnesota | 55414 | United States |
| Washington University in St. Louis | St Louis | Missouri | 63110 | United States |
| Albany Medical College | Albany | New York | 12020 | United States |
| Duke University Medical Center | Durham | North Carolina | 22705 | United States |
| Wake Forest University | Winston-Salem | North Carolina | 27157 | United States |
| Pennsylvania State University | Hershey | Pennsylvania | 17033 | United States |
| Ottawa Hospital Research Institute | Ottawa | K1Y 4E9 | Canada |
| Centre for Addiction and Mental Health | Toronto | M5T 2S8 | Canada |
| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| D019578 | Multiple System Atrophy |
| D013494 | Supranuclear Palsy, Progressive |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
| D054969 | Primary Dysautonomias |
| D001342 | Autonomic Nervous System Diseases |
| D009886 | Ophthalmoplegia |
| D015835 | Ocular Motility Disorders |
| D003389 | Cranial Nerve Diseases |
| D024801 | Tauopathies |
| D010243 | Paralysis |
| D009461 | Neurologic Manifestations |
| D005128 | Eye Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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