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Addressing cognitive deficits in alcohol use disorder (AUD) supports recovery. Impaired metacognitive functioning in AUD causes compromised recognition of the interoceptive state leading to the maintenance of alcohol abuse despite negative consequences. By promoting greater self-awareness and self-regulation, neurofeedback training is of high relevance in metacognition remediation to support abstinence.
The main objective of the present study is to validate neurofeedback as a complementary clinical tool to overcome metacognitive deficits that represent a significant factor in the maintenance of harmful consumption behavior and relapse phenomena in AUD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Active neurofeedback group | Experimental |
| |
| Placebo feedback group | Placebo Comparator |
| |
| Control group | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Neurofeedback active | Device | Neurofeedback uses real-time displays of brain activity to teach self regulation of brain function. People can learn to control their own brain activity through operant conditioning, where they receive feedback on their brainwaves and learn to modify them to achieve a desired state. Active neurofeedback group aims at enhancing the sensorimotor rhythm (12-15 Hz). |
| Measure | Description | Time Frame |
|---|---|---|
| Event related potential | Error related negativity (ERN) measurement | Baseline T0 |
| Event related potential | Error related negativity (ERN) measurement | Immediately after the last neurofeedback training session T1 |
| Metacognition questionnaire-30 (MCQ-30) | Metacognitive assessment by means of a questionnaire. Scores from 6 to 24, with higher scores meaning worse outcomes. | Baseline T0 |
| Metacognition questionnaire-30 (MCQ-30) | Metacognitive assessment by means of a questionnaire. Scores from 6 to 24, with higher scores meaning worse outcomes. | Immediately after the last neurofeedback training session T1 |
| Measure | Description | Time Frame |
|---|---|---|
| Commission error rate | Behavior assessment | Baseline T0 |
| Commission error rate | Behavior assessment | Immediately after the last neurofeedback training session T1 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Salvatore Campanella | Contact | 3224772705 | salvatore.campanella@chu-brugmann.be | |
| Clémence Dousset | Contact | clemence.dousset@ulb.be |
| Name | Affiliation | Role |
|---|---|---|
| Salvatore Campanella | CHU Brugmann | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Brugmann | Recruiting | Brussels | 1020 | Belgium |
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|
| Neurofeedback placebo | Device | Neurofeedback uses real-time displays of brain activity to teach self regulation of brain function. People can learn to control their own brain activity through operant conditioning, where they receive feedback on their brainwaves and learn to modify them to achieve a desired state. Placebo feedback group (PFT) : patients enhance random frequency bands |
|
| Reaction times | Behavior assessment | Baseline T0 |
| Abstinence | Number of days of abstinence | Immediately after the last neurofeedback training session T1 |
| Abstinence | Number of days of abstinence | 2 weeks post discharge |
| Abstinence | Number of days of abstinence | 1 month post discharge |
| Abstinence | Number of days of abstinence | 2 months post discharge |
| Abstinence | Number of days of abstinence | 3 months post discharge |
| ID | Term |
|---|---|
| D000437 | Alcoholism |
| ID | Term |
|---|---|
| D019973 | Alcohol-Related Disorders |
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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