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Prospective observational study evaluating the incidence, and qualifying the types, of perioperative pulmonary complications in patients that vape.
The primary objective of our study is to determine the rate at which patients that vape or use e-cigarettes experience perioperative pulmonary complications during and following general anesthesia. Complications of interest will include postoperative atelectasis with hypoxemia necessitating oxygen therapy, pneumothorax, pneumonia, bronchospasm, bronchospasm requiring bronchodilator therapy, exacerbation of underlying pulmonary disease, pneumonia, ARDS, and acute respiratory failure. Hospital course, including prolonged PACU stay, prolonged hospital admission for inpatients, and rate of ICU admissions, will also be investigated.
A secondary objective will be to further investigate and include the relationship between vaping cessation timeline in the preoperative period and the occurrence of PPCs, which is similarly underreported in the literature. Furthermore, the study will assess how effectively anesthesia providers are screening for vaping or e-cigarette use as part of the preoperative evaluation, given that "it is unclear whether anesthesiologists and surgeons routinely ask patients explicitly about vaping" in the pre-operative setting. This lack of representative screening for vaping further obscures an understanding of the relationship between vaping, vaping cessation, and PPCs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vaping patients | Includes patients that actively vape that are undergoing general anesthesia | ||
| Non-vaping patients | Includes patients that do not actively vape that are undergoing general anesthesia |
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| Measure | Description | Time Frame |
|---|---|---|
| Perioperative pulmonary complications | Complications of interest will include postoperative atelectasis with hypoxemia necessitating oxygen therapy, pneumothorax, pneumonia, bronchospasm, bronchospasm requiring bronchodilator therapy, exacerbation of underlying pulmonary disease, pneumonia, ARDS, and acute respiratory failure. Hospital course, including prolonged PACU stay, prolonged hospital admission for inpatients, and rate of ICU admissions, will also be investigated. | From the initiation of general anesthesia through postoperative day seven. |
| Measure | Description | Time Frame |
|---|---|---|
| Vaping cessation timeline | Includes the relationship between vaping cessation timeline in the preoperative period and the occurrence of postoperative pulmonary complications | From the initiation of general anesthesia through postoperative day seven. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients, both those that vape and those that do not, who meet the inclusion criteria and receive general anesthesia to facilitate surgical intervention at Naval Medical Center San Diego.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Naval Medical Center San Diego | San Diego | California | 92134 | United States |
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| ID | Term |
|---|---|
| D000072137 | Vaping |
| D000860 | Hypoxia |
| D001986 | Bronchial Spasm |
| D011014 | Pneumonia |
| ID | Term |
|---|---|
| D012907 | Smoking |
| D001519 | Behavior |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
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| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D008171 | Lung Diseases |