Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The goals of this pilot study are to assess the presence of harmful germs for gums and to assess oral health in adults with autism spectrum disorder.
Participants or their tutors will fulfill a form with general health information and daily habits.
Investigators will :
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adults with Autism Spectrum Disorder | Experimental |
|
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| collection of saliva, gum fluid and/or dental plaque samples | Other | Non-invasive sampling of dental plaque, crevicular fluid and/or saliva, using an examination probe, paper tips and saliva swabs |
| Measure | Description | Time Frame |
|---|---|---|
| Presence of periodontopathogenic bacteria (harmful for gums) | Technique used = Polymerase Chain Reaction (PCR) Measure unit = Colony-Forming Unit (CFU) | Collection on Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of the presence of parasites Entamoeba gingivalis subtype 1 (ST1) and subtype 2 (ST2) and Trichomonas tenax | Technique = Polymerase Chain Reaction (PCR) Unit = Colony-Forming Unit (CFU) | Collection on Day 1 |
| Assessment of the periodontal status of patients with Autism Spectrum Disorder |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Ludivine BERBE | CHRU Nancy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU Brabois | Vandœuvre-lès-Nancy | 54500 | France |
Not provided
| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| ID | Term |
|---|---|
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
Not provided
Not provided
Pilot study concerning adults with autism spectrum disorder
Not provided
Not provided
No Treatment
Not provided
Index used = the Dutch Periodontal Index 0 = minimum value, better outcome 4 = maximum value, worse outcome |
| Day 1 |
| Assessment of the dental condition | Dental data will be collected using the Decay-Missing-Filled/Teeth (DMFT) score 0 = minimum value, best outcome 28 = maximum value, worst outcome | Day 1 |
| Assessment of oral hygiene | Oral hygiene will be assessed using the Silness and Löe plaque index and the lifestyle questionnaire 0 = minimum value, best outcome 3 = maximum value, worst outcome | Day 1 |
| Collection of data about lifestyle habits (oral and dental hygiene, diet, activity, etc.) and drug treatments that may influence the clinical parameters observed | Data collection via a form fulfilled by the participant or the patient's legal guardian | Before samples collection and clinical examination |