Oral Microbiota and Oral Status of Adult Patients With Autism Spectrum Disorders (MICAA: MICrobiota Autism Adults)

Characterisation of the Oral Microbiota and Oral Status of a Population of Adult Patients With Autism Spectrum Disorders: a Pilot Study

The goals of this pilot study are to assess the presence of harmful germs for gums and to assess oral health in adults with autism spectrum disorder.

Participants or their tutors will fulfill a form with general health information and daily habits.

Investigators will :

• collect saliva, gum fluid and/ or dental plaque to characterise germs
• assess gum health and oral hygiene
• register decays, filled and missing teeth.

Inclusion Criteria:

• A person (or legal representative) who has received full information about the organisation of the research and accept to participate and the use of his or her data.
• Adult with autism spectrum disorder, men or women aged between 18 and 60.
• Member of a social security scheme or beneficiary of a medical insurance

Exclusion Criteria:

• Children under 18 with autism spectrum disorder
• Use of medication or situations that may affect the microbiota (use of antibiotics, probiotics, steroidal or non-steroidal anti-inflammatory drugs in the last 3 months, strict mouth breathing)
• Smoking
• Very lingual position of the teeth hindering clinical assessment of the periodontium
• Patients who have had periodontal treatment for less than 6 months
• Persons covered by articles L. 1121-5 to L. 1121-7 and L1122-2 of the French Public Health Code:
• Pregnant women, women in labour or breast-feeding mothers
• Persons deprived of their liberty by a judicial or administrative decision
• Persons unable to give their consent
• Person under psychiatric care by virtue of articles L. 3212-1 and L. 3213-1 of the Public Health Code
• Minor (not emancipated)