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The goal of this clinical trial study is to investigate comparing Effects of Beetroot juice and Mediterranean diet on Liver Enzymes and Sonographic appearance in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD)
The main question[s] it aims to answer are:
Patients with NAFLD were identified and enrolled for this research at the PAR hospital in the Kurdistan Region of Iraq.
For 12 weeks, for the group members who were receiving the MeD, we recommended consuming Mediterranean foods like fish, poultry, sources of omega-3, vegetables and colored fruits, legumes and nuts, and low-fat goods while avoiding inflammatory foods like high-fat foods, processed meats, fast food, simple sugars, chips, and soft drinks.
At baseline, the participants' demographic and anthropometric information, including as gender, age, weight, height, smoking status, location of residence, and physical activity, were recorded.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 250 ml of a placebo | Placebo Comparator | 250 ml of a placebo |
|
| beetroot juice (BJ) | Experimental | 250 ml of concentrated beetroot juice |
|
| Mediterranean diet with beet juice (BJ+MeD) | Experimental | Mediterranean diet with beet juice (BJ+MeD) |
|
| Mediterranean diet alone (MeD) | Experimental | Mediterranean diet alone (MeD) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Beetroot juice | Other | 250 ml of concentrated beetroot juice, were given to participants in the BJ groups .This was carried out in the morning, 30 minutes before breakfast, and on an empty stomach. |
| Measure | Description | Time Frame |
|---|---|---|
| Beetroot juice has role in reduce liver enzymes | Beetroot juice was given for 12 weeks and has role in reduce Serum Bilirubin, alkaline phosphatase (ALP), alanine transaminase (ALT), and liver enzyme was measured by blood sampling tests. | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Mediterranean diet contributes to lower liver enzyme levels. | Mediterranean diet was given for 12 weeks and has role in reduce Serum Bilirubin, alkaline phosphatase (ALP), alanine transaminase (ALT), and liver enzyme was measured by blood sampling tests. | 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hawal Lateef, Msc | Nursing department, sulaimany polytechni university, kurdistan, iraq | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hawal | Sulaymaniyah | Sulaimanyah | 46021 | Iraq |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37662597 | Derived | Fateh HL, Rashid SA, Muhammad SS, Al-Jaf SH, Ali AM. Comparing effects of beetroot juice and Mediterranean diet on liver enzymes and sonographic appearance in patients with non-alcoholic fatty liver disease: a randomized control trials. Front Nutr. 2023 Aug 17;10:1181706. doi: 10.3389/fnut.2023.1181706. eCollection 2023. |
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The participants were split into four groups: control, Mediterranean diet with beet juice (BJ+MeD), Mediterranean diet alone (MeD) and beetroot juice (BJ). The Mediterranean diet included fruits, vegetables, fish, poultry, and other lean meats (without skin), sources of omega-3 fatty acids, nuts, and legumes. Beetroot juice had 250 mg of beetroot.
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Statical analyser
| placebo | Other | 250 ml of a placebo |
|
| Mediterranean diet alone (MeD) | Other | Mediterranean diet alone (MeD) |
|
| Mediterranean diet with beet juice (BJ+MeD) | Combination Product | Mediterranean diet with beet juice (BJ+MeD). |
|
| ID | Term |
|---|---|
| D065626 | Non-alcoholic Fatty Liver Disease |
| ID | Term |
|---|---|
| D005234 | Fatty Liver |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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| ID | Term |
|---|---|
| D038441 | Diet, Mediterranean |
| ID | Term |
|---|---|
| D000095500 | Diet, Plant-Based |
| D004035 | Diet Therapy |
| D044623 | Nutrition Therapy |
| D013812 | Therapeutics |
| D004032 | Diet |
| D009747 | Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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