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Detection the relationship between preoperative ionized magnesium levels and the risk of acute kidney injury after cardiac surgery.
Acute kidney injury (AKI) is a major medical problem that is of particular concern after cardiac surgery. The reported prevalence of cardiac surgery-associated acute kidney injury (CSA-AKI) is up to 30% and is independently associated with an increase of morbidity and mortality .So this study is for measuring preoperative ionized magnesium levels of patients who will undergo cardiac surgeries then measuring postoperative serum creatinine, BUN and urine output to detect if they developed AKI or not and if there is a relationship between the post cardiac surgery AKI and preoperative ionized magnesium levels.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adults undergoing cardiac surgery without preoperative renal affection | Detect the preoperative magnesium levels in adults undergoing cardiac surgery without preoperative renal affection and follow up if they developed postoperative acute kidney injury or not. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| magnesium levels | Other | Detection of the relationship between cardiac surgery associated AKI and preoperative magnesium levels. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Post cardiac surgery AKI according to KDIGO criteria with low preoperative magnesium level | Measuring preoperative magnesium level and postoperative kidney functions in form of serum creatinine in umol/L , BUN in mmol/L and urine output ml/h to detect the relationship between preoperative low magnesium level and risk of acute kidney injury after cardiac surgery. | Baseline |
| Post cardiac surgery AKI according to KDIGO criteria with normal or high preoperative magnesium level | Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery. | basline |
| Post cardiac surgery normal kidney functions with low preoperative magnesium level | Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery. | basline |
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Inclusion Criteria:
Exclusion Criteria:
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people more than or equal 18 years who undergo open heart surgery between July 2023 to July 2024 and not known to have kidney disease .
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mostafa Ahmed | Contact | 01113038074 | mostafakaleed21@gmail.com | |
| Samir Kamal | Contact | 01062949199 | samirkotb45@yahoo.com |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35469966 | Background | Koh HB, Jung CY, Kim HW, Kwon JY, Kim NH, Kim HJ, Jhee JH, Han SH, Yoo TH, Kang SW, Park JT. Preoperative Ionized Magnesium Levels and Risk of Acute Kidney Injury After Cardiac Surgery. Am J Kidney Dis. 2022 Nov;80(5):629-637.e1. doi: 10.1053/j.ajkd.2022.03.004. Epub 2022 Apr 23. |
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| ID | Term |
|---|---|
| D001806 | Blood Urea Nitrogen |
| ID | Term |
|---|---|
| D001774 | Blood Chemical Analysis |
| D019963 | Clinical Chemistry Tests |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
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|
| D003933 | Diagnosis |
| D007677 | Kidney Function Tests |
| D003950 | Diagnostic Techniques, Urological |
| D008919 | Investigative Techniques |