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• Transient hypothyroxinemia of prematurity (THoP) is defined as free thyroxine (FT4) level is below the reference values despite normal TSH level in preterm infant. This study aims to evaluate the neurological development of infants with transient premature hypothyroxinemia (THoP).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Case | Infants with THoP |
| |
| Control | Healthy infants |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 'Ages and Stages Questionnaries' (ASQ) | Other | ''ASQ' is a screening tool for assessing the development of infants and preschoolers in the areas of communication, fine motor, gross motor, problem-solving and personal-social development, and 'ASQ:SE' is a screening tool for social-emotional development |
| Measure | Description | Time Frame |
|---|---|---|
| Long-term Neurodevelopment | 'Ages And Stages Questionnaires' (ASQ) 'Ages And Stages Questionnaires: Social-Emotional' (ASQ:SE) Developmental Screening Tests evaluates the areas of communication, fine motor, gross motor, problem-solving and personal-social development. ASQ score differs 0-60 and results are interpreted in three group according to the gained points as normal, risky, and follow-up required. | 5 years |
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Inclusion Criteria:
Exclusion Criteria:
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This study included newborn infants born at 28-36 gestational weeks, with a diagnosis of transient hypothyroxinemia of prematurity, and hospitalized in the neonatal intensive care unit. Healthy age-matched infants were included in the control group.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul Kanuni Sultan Suleyman Training and Research Hospital | Istanbul | 34303 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D017127 | Glycation End Products, Advanced |
| D004864 | Equipment and Supplies |
| ID | Term |
|---|---|
| D006001 | Glycoconjugates |
| D002241 | Carbohydrates |
| D014118 | Toxins, Biological |
| D001685 | Biological Factors |
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