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The goal of this clinical trial is to learn about Whether carotid ultrasound guided fluid management can reduce the incidence of hypotension after general anesthesia induction in elderly patients undergoing gastrointestinal surgery.
The main question[s] it aims to answer are:
Whether fluid therapy reduces the incidence of general anaesthesia induced hypotension in elderly patients undergoing gastrointestinal surgery.
Whether carotid ultrasound can guide fluid management in elderly patients undergoing gastrointestinal surgery.
Participants will use carotid ultrasound to assess volume status. If volume is insufficient, fluid therapy will be selected until volume is sufficient, anesthesia will be then induced. If volume is sufficient, anesthesia will be directly induced. There is a comparison group: No carotid ultrasound will be used to assess the volume status of the patients, and anesthesia will be directly induced.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| B-Carotid ultrasound guided fluid therapy | Experimental | Participants will use carotid ultrasound to assess volume status. If volume is insufficient, fluid therapy will be selected until volume is sufficient, anesthesia will be then induced. If volume is sufficient, anesthesia will be directly induced. |
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| C-No intervention | No Intervention | No carotid ultrasound will be used to assess the volume status of the patients, and anesthesia will be directly induced. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fluid therapy under the guide of Carotid ultrasound | Other | Participants will use carotid ultrasound to assess volume status. If volume is insufficient, fluid therapy will be selected until volume is sufficient. If volume is sufficient, no fluid therapy will be given. |
| Measure | Description | Time Frame |
|---|---|---|
| Occurrence of hypotension after anesthesia induction | Hypotension occurred from anesthesia induction to 20 minutes after induction in both groups. | General anesthesia induction from the beginning to 20 minutes after induction |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative acute kidney injury | Postoperative creatinine increased for a short period of time to more than 0.3mg/dl (26.5μmol/L) or to more than 1.5 times the preoperative creatinine concentration. | Within 7 days after surgery |
| postoperative delirium |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jingfeng Bai | Contact | 15773490489 | bjf159323@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Su Min | First Affiliated Hospital of Chongqing Medical University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| China,Chongqing The First Affiliated Hospital of Chongqing Medical University | Recruiting | Chongqing | Chongqing Municipality | 400016 | China |
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This is a randomized controlled clinical study to investigate whether carotid ultrasound-guided fluid therapy reduces the incidence of induced hypotension in elderly patients undergoing gastrointestinal surgery.
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In this study, researchers and subjects were not blind. Anesthesiologists and data collectors were blind. Researchers conducted carotid ultrasound guided fluid therapy for experimental groups according to the groups, anesthesiologists performed routine induction for patients in the two groups, data collectors collected data, and anesthesiologists and data collectors did not know the groups of subjects.
Newly diagnosed delirium by the psychiatric department within 30 days after surgery |
| Within 30 days after surgery |
| postoperative stroke | Any newly diagnosed postoperative neurological dysfunction within 30 days after surgery. | Within 30 days after surgery |