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| Name | Class |
|---|---|
| West African Consortium for Clinical Research on Epidemic Pathogens (WAC-CREP) | UNKNOWN |
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This community-based mixed methods study intends to identify, explore, and assess the determinants of community preparedness for outbreak situations, including acceptance for Ebola vaccines.
This community-based study intends to identify, explore, and assess the determinants of community preparedness for outbreak situations and acceptance for the administration of Ebola vaccination. The investigators will conduct an anthropologically driven mixed methods study design that comprises both qualitative and quantitative research methods for the successful implementation of this community-based study. The investigators will conduct structured interviews with community members and local responders to broadly assess and understand the perspectives regarding appropriate strategies previously employed to effectively support community preparedness during outbreak response and also to broadly access and understand appropriate strategies previously employed to effectively support community acceptance for Ebola vaccines, respectively. Learning from the experiences of local voices produces globally emergent systems that are trusted, reliable and sustainable.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cluster 1 | Communities highly affected and impacted by EVD |
| |
| Cluster 2 | Communities not highly affected and impacted by EVD |
| |
| Cluster 3 | Communities receptive to EVD vaccination |
| |
| Cluster 4 | Communities resistance to EVD vaccination |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Community Clusters | Behavioral | Assessment of the determinants for community preparedness to EVD outbreaks and acceptance of EVD vaccines. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Measure #1 | Assess Community Preparedness with the Resiliency Scale | 2 Years |
| Measure #2 | Assess Community Acceptance of EVD Vaccine with the Resiliency Scale | 2 Years |
| Measure | Description | Time Frame |
|---|---|---|
| Measure #3 | Assess Roles of Community Leaders with the Resiliency Scale | 2 Years |
| Measure #4 | Assess Roles of Formal and Informal Community Structures with the Resiliency Scale |
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Inclusion Criteria:
Exclusion Criteria:
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Health adults (males and females)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Stephen B Kennedy, MD, MPH | Contact | +231770645830 | sbkennedy4@gmail.com | |
| Hannah Berrian, MPH | Contact | +231777938203 | hannahberrian@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Stephen B Kennedy, MD, MPH | UL-PIRE Africa Center, University of Liberia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Montserrado, Margibi and Lofa Counties | Monrovia | Montserrado County | 1000 | Liberia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26768572 | Result | Kennedy SB, Neaton JD, Lane HC, Kieh MW, Massaquoi MB, Touchette NA, Nason MC, Follmann DA, Boley FK, Johnson MP, Larson G, Kateh FN, Nyenswah TG. Implementation of an Ebola virus disease vaccine clinical trial during the Ebola epidemic in Liberia: Design, procedures, and challenges. Clin Trials. 2016 Feb;13(1):49-56. doi: 10.1177/1740774515621037. Epub 2016 Jan 14. | |
| 25974635 |
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| ID | Term |
|---|---|
| D019142 | Hemorrhagic Fever, Ebola |
| ID | Term |
|---|---|
| D006482 | Hemorrhagic Fevers, Viral |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D007239 | Infections |
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|
| 2 Years |
| Nyenswah T, Fallah M, Sieh S, Kollie K, Badio M, Gray A, Dilah P, Shannon M, Duwor S, Ihekweazu C, Cordier-Lassalle T, Shinde SA, Hamblion E, Davies-Wayne G, Ratnesh M, Dye C, Yoder JS, McElroy P, Hoots B, Christie A, Vertefeuille J, Olsen SJ, Laney AS, Neal JJ, Yaemsiri S, Navin TR, Coulter S, Pordell P, Lo T, Kinkade C, Mahoney F; Centers for Disease Control and Prevention (CDC). Controlling the last known cluster of Ebola virus disease - Liberia, January-February 2015. MMWR Morb Mortal Wkly Rep. 2015 May 15;64(18):500-4. |
| 17762021 | Result | O'Dowd A. Infectious diseases are spreading more rapidly than ever before, WHO warns. BMJ. 2007 Sep 1;335(7617):418. doi: 10.1136/bmj.39318.516968.DB. No abstract available. |
| 25558097 | Result | Kennedy SB, Nisbett RA. The Ebola epidemic: a transformative moment for global health. Bull World Health Organ. 2015 Jan 1;93(1):2. doi: 10.2471/BLT.14.151068. No abstract available. |
| 29945597 | Result | Fregonese F. Community involvement in biomedical research conducted in the global health context; what can be done to make it really matter? BMC Med Ethics. 2018 Jun 15;19(Suppl 1):44. doi: 10.1186/s12910-018-0283-4. |
| 15983268 | Result | Dickert N, Sugarman J. Ethical goals of community consultation in research. Am J Public Health. 2005 Jul;95(7):1123-7. doi: 10.2105/AJPH.2004.058933. Epub 2005 Jun 16. |
| 11009541 | Result | Wills C, Tyeku V. Community participation is essential in clinical trials. BMJ. 2000 Sep 30;321(7264):833. No abstract available. |
| 27382077 | Result | Esangbedo DO, Ughasoro MD, Tagbo BN, Olowu A, Anikene C, Iwegbulam CC. Health-Care Workers' Perspectives on Ebola Virus Vaccine: A Focus Group and In-Depth Interview Interventional Study. Am J Trop Med Hyg. 2016 Sep 7;95(3):654-62. doi: 10.4269/ajtmh.16-0206. Epub 2016 Jul 5. |
| 33938368 | Result | Chiam AL, Cheng NWI, Larson H. Community engagement for outbreak preparedness and response in high-income settings: A systematic review. Glob Public Health. 2022 Jul;17(7):1113-1135. doi: 10.1080/17441692.2021.1919734. Epub 2021 May 2. |
| 30855742 | Result | PREVAIL III Study Group; Sneller MC, Reilly C, Badio M, Bishop RJ, Eghrari AO, Moses SJ, Johnson KL, Gayedyu-Dennis D, Hensley LE, Higgs ES, Nath A, Tuznik K, Varughese J, Jensen KS, Dighero-Kemp B, Neaton JD, Lane HC, Fallah MP. A Longitudinal Study of Ebola Sequelae in Liberia. N Engl J Med. 2019 Mar 7;380(10):924-934. doi: 10.1056/NEJMoa1805435. |
| D018702 |
| Filoviridae Infections |
| D018701 | Mononegavirales Infections |