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This observational study aims to identify the determinants or predictors of postoperative atrial fibrillation (POAF) in patients who have undergone coronary artery bypass grafting (CABG). The study will compare two cohorts: patients who developed POAF and those who did not (non-POAF), with the aim of improving postoperative care, reducing complications, and refining patient risk stratification.
Demographics (age, sex, ethnicity), lifestyle factors (smoking, alcohol, physical activity), and medical history (diabetes, hypertension, prior heart diseases) will be recorded. Surgical procedure details (number of grafts, use of intraoperative devices), anesthesia, and medications administered. Levels of inflammatory markers, cardiac-specific markers, and other relevant biomarkers at baseline and postoperatively. Other complications besides POAF, hospital length of stay, ICU admission, readmission rate, and mortality will also be monitored.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| POAF | This group will consist of patients who have developed postoperative atrillary fibrillation (POAF) after undergoing coronary artery bypass grafting (CABG). |
| |
| Non-POAF | This group will consist of patients who have not developed postoperative atrillary fibrillation (POAF) after undergoing coronary artery bypass grafting (CABG). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CABG | Procedure | All participants in the study will undergo the standard procedure of CABG. Continuous electrocardiogram monitoring and electrocardiography were used to identify the cardiac rhythm. |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of POAF | This will be determined based on electrocardiograms (ECG) and/or relevant medical records, within 30 days post-CABG. | During hospital stay, up to 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Hospital length of stay | During hospital stay, up to 30 days | |
| ICU admission time | During hospital stay, up to 30 days | |
| Number of participants with Stroke |
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Inclusion Criteria:
Exclusion Criteria:
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The participants in this study are adult patients (18 years and older) who have undergone Coronary Artery Bypass Grafting (CABG). These individuals come from diverse demographic backgrounds and have a history of severe coronary heart disease, the condition that necessitated the CABG surgery.
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| Name | Affiliation | Role |
|---|---|---|
| Kun Hua, MD | Beijing Anzhen Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beijing Anzhen Hospital | Beijing | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41659092 | Derived | Zhou X, Pan Y, Hua K, Yang X. Impact of Sodium-Glucose Cotransporter 2 Inhibitors on Acute Kidney Injury Post Off-Pump Coronary Artery Bypass Grafting: A Retrospective Cohort Study and Meta-Analysis. Rev Cardiovasc Med. 2026 Jan 21;27(1):39400. doi: 10.31083/RCM39400. eCollection 2026 Jan. |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| During hospital stay, up to 30 days |
| Mortality | During hospital stay, up to 30 days |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |