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This is a prospective, observational clinical study with150 patients of persistent AF (trial group 1), 150 patients of paroxysmal AF (trial group 2), and 150 healthy subjects (control group). The trial is divided into two parts. The aim of first part is to evaluate the sensitivity and specificity of magnetocardiography on diagnosing persistent AF, and the second part is to evaluate the independent predictors of magnetocardiography on predicting recurrence of paroxysmal AF. The patients who had been diagnosed with AF in OPD or IPD will be included. After signing the informed consent letter, medical history of all subjects will be collected, including magnetic cardiogram, 12-lead electrocardiogram, holter electrocardiogram, cardiac ultrasound and blood tests. Patients with paroxysmal AF will be followed up for 3 months, and the recurrence of AF is the observation end point.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1: Persistent AF |
| ||
| Group 2 : Paroxysmal AF |
| ||
| Healthy controls |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Magnetocardiography | Device | Magnetocardiography is a device used to exam the dynamic magnetic map of the heart for the diagnosis of some heart diseases |
|
| Measure | Description | Time Frame |
|---|---|---|
| sensitivity and specificity | The sensitivity and specificity of magnetocardiography in the diagnosis of persistent AF | 24 hours |
| Independent predictors of recurrence of paroxysmal atrial fibrillation | A statistical model is used to obtain the magnetocardiographic parameters that could predict the recurrence of paroxysmal atrial fibrillation. | 3 months |
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Group: Group 1 (Persistent AF)
Inclusion criteria:
Exclusion criteria:
Group: Group 2 (Paroxysmal AF)
Inclusion criteria:
Exclusion criteria:
Group: Control group
Inclusion criteria:
Exclusion criteria:
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Patients with atrial fibrillation and healthy people without arrhythmia
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jian'an Wang | Contact | +86-13805786328 | wangjianan111@zju.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Jian'an Wang | Second Affiliated Hospital, School of Medicine, Zhejiang University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Second Affiliated Hospital, Zhejiang University School of Medicine | Recruiting | Hangzhou | Zhejiang | 310009 | China |
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D053798 | Magnetocardiography |
| ID | Term |
|---|---|
| D006334 | Heart Function Tests |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D004568 | Electrodiagnosis |
| D060306 | Magnetometry |
| D008919 | Investigative Techniques |
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