Improving the Early Detection of Cardiometabolic Disease Risk

A Multi-Modal Approach to Improving the Early Detection of Cardiometabolic Disease Risk

The goal of this observational study is to reduce an individual's cardiometabolic disease risk by improving the ability to detect cardiometabolic disease risk in young adults through the use of novel technologies that increase access to and examine the utility of, a continuous metabolic syndrome severity score. An additional goal of this study is to understand the barriers to engagement in health-promoting behaviors and beliefs about interventions aimed at mitigating metabolic syndrome risk through a brief online lifestyle intervention.

The main question[s] it aims to answer are:

• Can a smartphone-based imaging system accurately predict a continuous metabolic syndrome severity score, in addition to other markers of cardiometabolic disease, in young adults?
• What is the relationship between autonomic dysfunction and metabolic syndrome severity in a cohort of young adults?
• What is the relationship between peripheral vascular dysfunction and metabolic syndrome severity in a cohort of young adults?
• What are the associations between metabolic syndrome severity and gait and functional ability in young adults using novel markerless motion capture technology?
• What are the attitudes and barriers towards lifestyle interventions targeted to reduce metabolic syndrome severity?
• What are the treatment-seeking and willingness to engage behaviors toward a webpage focused on lifestyle interventions to reduce metabolic syndrome severity?

Participants will be asked to undergo several assessments across four separate days which are design designed to determine the associations between cardiometabolic health markers and components of:

• body composition
• cardiovascular function
• functional ability
• attitudes and behaviors towards health-related interventions

Inclusion Criteria:

- adults between the ages of 18-39 years of age

Exclusion Criteria:

• Younger than 18 or older than 39
• Pregnant
• Breastfeeding or lactating
• Missing any limbs or part of a limb
• Having a substantial amount of metal implants (metal plates or complete joint replacements)
• Having a pacemaker or any other electrical implant
• Type I diabetes
• Gestational diabetes
• Taking insulin
• Diagnosed heart failure, cardiomyopathy (dilated or hypertrophic), valvular disease
• Any history of severe traumatic brain injury or mild traumatic brain injury within the last two years
• Kidney disease
• Liver disease
• Thyroid disease
• Any diagnosed neurological or neurodegenerative diseases
• Having received ionizing radiation from a medical procedure within the last 30 days
• Being on a medically prescribed diet
• Having donated blood or plasma in the last 20 days prior to blood collection procedures
• Taking any supplements/medications that may interfere with the results of the study
• Any injury or physical impairment that would prevent performing any functional measures for this study