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Chronic pain is a common complication after cardiothoracic surgery. The prevalence of post-sternoyomy pain syndrome (PSPS) ranges from 33% to 91%. Exact pathogenetic mechanisms for developing chronic pain after sternotomy are unknown. Apart from intraoperative nerve damage and subsequent postoperative neuropathic pain, operation techniques, age, sex, pre-existing pain, genetic and psychosocial factors, severe postoperative pain, and analgesic management are suspected to have an impact on the development of PSPS .
Ultrasound-guided Pecto-intercostal Fascial Block (PIFB) has been advocated by some researchers for cardiac surgery. Pecto-intercostal fascial plane block (PIFB) is a novel, minimally invasive, regional fascial plane block technique. PIFB was first described by de la Torre in patients undergoing breast surgery . PIFB targets the anterior intercostal nerves as they run in the fascial plane between the pectoral and the intercostal muscles and emerge on either side of the sternum.
Also, lidocaine, a short-acting local anesthetic, has been proved to have analgesic and anti-inflammatory effects . The application of lidocaine by continuous infusion in the intraoperative period and immediately after the surgery appears to reduce the immediate postoperative pain, and may prevent the PSPS
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PIFB group | Active Comparator | patients will receive bilateral ultrasound-guided pecto-intercostal fascial block using 20 ml of bupivacaine 0.25% for each side. |
|
| LIDOCAINE group | Active Comparator | 1.5 mg/kg lidocaine will be administered after induction of anesthesia, then 2mg/kg/h lidocaine will be administered with continuous intravenous infusion until the end of the surgery. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| pecto intercostal fascial block using bupivacaine 0.25% | Procedure | patients will receive bilateral ultrasound-guided pecto-intercostal fascial block using 20 ml of bupivacaine 0.25% for each side. |
| Measure | Description | Time Frame |
|---|---|---|
| Total dose of morphine in the first 24 h postoperatively. | total morphine consumed in the first 24 hour | 24 hours postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| NRS numerical rating scale. | NRS ranging from grade 0 (no pain) to grade 10 (most severe pain) NRS< 4 is acceptable for pain relief | 24 hours post operative |
| chronic postoperative pain in 3 months after operation according to numerical rating scale |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mariana A soliman, lecturer | Contact | 01222960009 | mrmrsyk4@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Mariana A mansour, Lecturer | benisuef university hospital,Egypt | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Benisuef University Hospital | Recruiting | Banī Suwayf | e\EYGPT | Egypt |
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| ID | Term |
|---|---|
| D008012 | Lidocaine |
| ID | Term |
|---|---|
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 |
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| lidocaine infusion | Drug | 1.5 mg/kg lidocaine will be administered after induction of anesthesia, then 2mg/kg/h lidocaine will be administered with continuous intravenous infusion until the end of the surgery. |
|
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NRS ranging from grade 0 (no pain) to grade 10 (most severe pain) NRS< 4 is acceptable for pain relief
| within 3 months postoperative |
| Time to rescue analgesic | time from extubation to the time the patiants given analgesia | within 24 hour postoperative |
| time to extubation | from end of surgery to the time of extubation | within 24 hour post operative |
| length of intensive care stay | from end of surgery to the time of discharging to the surgical word | within one week |
| Aniline Compounds |
| D000588 | Amines |