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To explore the predictive and diagnostic role of biomarkers in patients with neurological diseases.
With the rise and continuous development of omics technology and bioinformatics technology, some scholars have applied proteomics technology and metabolomics technology to study the brain tissue, plasma and CSF of patients with nervous system diseases, so as to screen out potential biomarkers, with a view to providing new research ideas for pathogenesis and early diagnosis of neurological diseases. At present, the research on some novel biomarkers is still in its infancy, and many key problems remain to be solved. It is necessary to further determine the expression level of biomarkers in normal human body and the characteristics of biomarkers in patients with neurological diseases.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients admitted to hospital/emergency department with neurological diseases | All clinical data, laboratory data and imaging data of patients at baseline and follow-up were collected, as well as blood and tissue samples that did not affect the diagnosis and treatment of patients after obtaining the consent of patients at different time points in the acute and chronic phases. |
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| Measure | Description | Time Frame |
|---|---|---|
| mRS score in 90 days | The proportion of 3-month good functional outcome (mRS Score 0-2) in patients with neurological diseases was evaluated by mRS Score | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with neurological diseases admitted to hospital/emergency department.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yi YY Yang, Ph.D. | Contact | 18186872986 | 86 | doctoryangyi@163.com |
| Zhen-Ni GZ GUO, M.D. | Contact | 18186872986 | 86 | zhen1ni2@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| First Hospital of Jilin University | Recruiting | Changchun | Jilin | 130000 | China |
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