Mindfulness-oriented Recovery Enhancement (MORE) for Cancer Pain Relief

Adapting Mindfulness-oriented Recovery Enhancement (MORE) for Cancer Pain Relief: The MORE Relief Trial

The purpose of this study is to evaluate whether or not mindfulness-based interventions/MBIs may help reduce chronic pain in participants who have cancer-related chronic pain. MBIs are therapeutic programs that use mindfulness meditation practices to help people focus on the present moment, as well as encourage acceptance of thoughts, emotions, and body sensations. The researchers think that an MBI treatment called Mindfulness-oriented Recovery Enhancement (MORE) may help people who are experiencing cancer-related chronic pain.

Inclusion Criteria:

• English speaking
• Age ≥ 18 years or older
• A history of cancer with no restrictions placed on type of cancer
• Determined to be either no-evidence of disease or stable oncological disease by referring or study physicians/advanced practice providers
• Having a pain (musculoskeletal, generalized, or neuropathic) rating of 4 or greater in worst pain on a 0-10 numerical rating scale in the preceding week
• Having had pain for at least 3 months and at least 15 days with pain in the preceding 30 days
• Willing to adhere to all study-related procedures, including randomization to one of two treatment arms: MORE or WLC
• Ability to attend video-call session and a quiet/private location

Exclusion Criteria:

• Active suicidality or schizophrenia
• Plan to initiate palliative radiation or interventional pain procedure within the next 12 weeks
• Cognitive impairment preventing completing PRO independently or participate in virtual MORE as evaluated by study clinicians