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The goal of this longitudinal study is to learn more about the articulatory consequences of surgical oral cancer treatment. The main aims are to study the coordination and development of speech articulation of patients who will undergo surgical treatment for oral cancer longitudinally and whether individual differences in the reliance on auditory or tactile information can predict the success of speech compensatory strategies.
Participants will perform multiple speech tasks while motion tracking sensors track the articulatory gestures.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Individuals treated for oral cancer | Dutch native speakers (18+) who will undergo surgical treatment for a T1 or T2 tumour on the tongue. |
| |
| Control speakers | Dutch native speakers (18+) without self-reported speech problems. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electromagnetic Articulography | Other | Motion tracking sensors will track articulatory movements of the tongue, jaw and lips |
|
| Measure | Description | Time Frame |
|---|---|---|
| Articulatory gestures | Articulatory movements in three dimensions of the tongue, lips and jaw as measured by the NDI Vox Electromagnetic Articulograph. Measures include: articulator speed (mm/s), total displacement (mm), coordinates (x,y,z) during specific gestures. | 2022-2025 |
| Acoustic outcomes | Speech acoustics will be measured in Praat and include the first and second formants of vowels (in Hz), global movement size in terms of acoustic working space (Hz-squared), and the centre of gravity of sibilants (in Hz) | 2022-2025 |
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Inclusion Criteria:
Exclusion Criteria:
1a. Recurrence of disease (for patients)
1b. Treated for oral cancer (for healthy controls) 2. Speech problems (e.g., stuttering) 3. Problems with sight or hearing that impede reading or understanding instructions. When glasses or a hearing aid resolve these problems, then participants are not excluded.
4. Neurological or psychological disorders (e.g., stroke) 5. Non-removable metal in, on or around the head (piercings, braces, pacemaker, electrodes) 6. Self-reported signs of depression
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Adults with and without oral cancer who speak Dutch as their native language
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Thomas Tienkamp, MA | Contact | +31 50 36 37051 | t.b.tienkamp@umcg.nl | |
| Max Witjes, PhD | Contact | +31 (0)50 361 3841 | m.j.h.witjes@umcg.nl |
| Name | Affiliation | Role |
|---|---|---|
| Max Witjes, PhD | University of Groningen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Arts, University of Groningen | Recruiting | Groningen | 9712 EK | Netherlands |
Will share where legally possible.
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| ID | Term |
|---|---|
| D000077195 | Squamous Cell Carcinoma of Head and Neck |
| D013064 | Speech Disorders |
| ID | Term |
|---|---|
| D002294 | Carcinoma, Squamous Cell |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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| University Medical Centre Groningen | Recruiting | Groningen | 9713 GZ | Netherlands |
|
| D009369 | Neoplasms |
| D006258 | Head and Neck Neoplasms |
| D009371 | Neoplasms by Site |
| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |