Effect of Inhaled Nitric Oxide on Pulmonary Ventilation/Perfusion Ratio Assessed by EIT in Patients With ARDS

Effect of Inhaled Nitric Oxide on Pulmonary Ventilation/Perfusion Ratio Assessed by Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrome

Electrical impedance tomography was used to monitor changes in pulmonary perfusion distribution and V/Q ratio before and after iNO in patients with acute respiratory distress syndrome to investigate the factors predicting iNO reactivity and the physiological mechanism underlying changes in oxygenation.

Inclusion Criteria:

1. Patients aged ≥ 18 years;
2. Patients are intubated and mechanically ventilated.

Exclusion Criteria:

1. EIT contraindications such as chest wound dressing, pacemaker installation, defibrillator, etc;
2. With a history of cerebral hemorrhage in the past half year, as well as bleeding in any site of the body;
3. Pneumothorax;
4. Medium or massive pleural effusion;
5. Refractory shock;
6. Pregnant
7. With chronic kidney disease
8. Atrial fibrillation or other malignant arrhythmia leads to a decrease in cardiac output;
9. Failure to sign informed consent