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Malignant Pleural Effusion (MPE) is considered to be a common presentation at malignant tumors representing 15% of all cancer cases. It carries a burden on our patients with dyspnea being the most common symptom in most of cases.
Management of symptomatic malignant pleural effusion remains to be a point of debate. Data available from literature shows conflicting results lacking high quality evidence which necsscitates further research work. Options differs to include chemical pleurodesis using medical or surgical talc poudrage or slurry. Surgical intervention with abrasion pleurodesis or pleurectomy using VATS approach has been used in many studies. Using indwelling pleural catheters (IPCs) has also proved comparable efficacy at many clinical trials. In this study we want to help answering this question so that we can add to the current knowledge aiming to offer the best care for those patients
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| VATS surgical pleurodesis | Other | Patients in whom we use VATS-surgical pleurodesis for malignant pleural effusion. |
|
| Tube drainage | Other | Patients in whom we use tube drainage for malignant pleural effusion. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| VATS-Surgical pleurodesis | Procedure | VATS drainage and surgical abrasion. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Total hospital stay | duration of hospital stay in days | 3 months postoperative |
| duration of airleak | duration in days | 3 months postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Status of performance | patient reported outcome through a pre-prepared questionnaire | 3 months |
| mortality | Rate of mortality | '3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kareem A Hosny, M.SC | Contact | 01000401994 | kareemdna94@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assiut university heart hospital | Recruiting | Asyut | 2112 | Egypt |
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Randomised Clinical Trial with 2 groups; Case group for VATS mechanical abrasion and Control group for tube drainage
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| Tube Drainage |
| Procedure |
Tube drainage for malignant pleural effusion |
|
| Failure of management | time to re-collection | 3 months |
| ID | Term |
|---|---|
| D016066 | Pleural Effusion, Malignant |
| ID | Term |
|---|---|
| D010997 | Pleural Neoplasms |
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D010996 | Pleural Effusion |
| D010995 | Pleural Diseases |
| D012140 | Respiratory Tract Diseases |
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