Effect of Different Remineralization Gels | NCT05868603 | Trialant

Effect of Different Remineralization Gels | NCT05868603 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Remineralization gel with CPP- ACP (GC Tooth MousseTM, Tokyo, Japan)	Experimental	CPP-ACP containing remineralization gel (Tooth Mousse GC, Tokyo, Japan) will be put into the Essix appliance with a reservoir and applied for 5-7 minutes twice a day for one month. Before and after the applying remineralization gel, the laser fluorescence values will measure with a DIAGNOdent pen (KaVo Dental corporation, East Main street Lake Zurich, lL).	Other: Remineralization gel
Remineralization gel with calcium glycerophosphate (R.O.C.S.® Medical Mineral Gel, Russia)	Experimental	Remineralization gel containing calcium glycerophosphate (R.O.C.S.® Medical Minerals Gel, Russia) will be put into the Essix appliance with a reservoir for 5-7 minutes twice a day for one month. Before and after the applying remineralization gel, the laser fluorescence values will measure with a DIAGNOdent pen( KaVo Dental corporation, East Main street Lake Zurich, lL).	Other: Remineralization gel
Control Group	No Intervention	No intervention.

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Remineralization gel	Other	Remineralization gel	Remineralization gel with CPP- ACP (GC Tooth MousseTM, Tokyo, Japan) Remineralization gel with calcium glycerophosphate (R.O.C.S.® Medical Mineral Gel, Russia)

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP)	Decrease in laser fluorescence values with Diagnodent Pen as an indicator of remineralization	4 weeks

Contacts/Locations Module